猪圆环病毒2型分子致病机理及相关疾病研究进展  

Studying on the Development of Molecular Pathogenesis and Related Infectious Disease in Porcine Circle Virus 2

作　　者：乔翠[1] 高凤山[1] 许崇波[1,2] 

机构地区：[1]大连大学生命科学与技术学院,辽宁大连116622 [2]大连大学医学院,辽宁大连116622

出　　处：《中国畜牧兽医》2012年第2期170-173,共4页China Animal Husbandry & Veterinary Medicine

摘　　要：猪圆环病毒(porcine circovirus,PCV)有两个基因型,分别为PCV1和PCV2。PCV2有致病性,它可以引发多种相关的疾病(PCVAD),如断奶后多系统衰竭综合征(PMWS)等。该病毒主要通过攻击猪的淋巴细胞,产生免疫抑制,诱发细胞凋亡,还可以和其他病毒协同感染,大大增加了动物的发病率及死亡率。文章对PCV2分子致病机理及引起的相关疾病和防治作一综述。Porcine circle virus has two genotypes,PCV1 and PCV2.Between them,only PCV2 is pathogenic and it can cause a variety of related diseases（PCVAD）,such as PMWS.PCV2 mainly attacks the lymphatic cells,and then to cause immune suppression and to induce apoptosis.PCV2 can also infect animals along with other virus,which greatly increases the animal＇s disease incidence rate and mortality rate.Now we will make a review on molecular character and pathogenesis of PCV2.

关 键 词：PCV2 PCVAD 淋巴免疫细胞 细胞凋亡 协同感染 

分 类 号：S852.65[农业科学—基础兽医学]