心血管高危住院患者治疗状况调查  

A survey of the medical treatment in hospitalized high-risk cardiovascular patients

作　　者：刘向东 唐海荣 胡大一[1,2] 李觉[3] 余金明[3] 布艾加尔·哈斯木 

机构地区：[1]江苏省南京明基医院心内科,江苏南京210019 [2]北京大学人民医院心脏中心,北京100041 [3]同济大学医学院,上海200092

出　　处：《实用临床医药杂志》2012年第1期114-116,共3页Journal of Clinical Medicine in Practice

基　　金：中国高校医学期刊临床专项资金(41120010)

摘　　要：目的调查心血管高危住院患者抗血小板药物、他汀类药物和血管紧张素转化酶抑制剂(ACEI)的应用情况。方法测定5 254例50岁以上心血管高危的住院患者的踝臂指数(ABI),ABI<0.9诊断为下肢动脉疾病(PAD);将患者分成单纯PAD组、单纯冠心病(CHD)组、单纯缺血性脑卒中(IS)、单纯糖尿病(DM)组,PAD合并CHD或IS或DM组和参照组,分析各组用药情况。结果 5 254例患者中仅65.4%、36.9%、46.9%的患者接受抗血小板药物、他汀类药物和ACEI治疗。单纯PAD组中,3种药物单用和合用比例明显低于单纯CHD组;3药合用仅见于56%的CHD,8%的单纯IS,13%的单纯DM和21%的单纯PAD患者。结论 PAD治疗情况远远不如CHD,因此动脉粥样硬化不同表现形式及DM急需得到规范的强化治疗。Objective To investigate into the use of antiplatelet agents,statins and angiotensin converting enzyme inhibitor（ACEI） in hospitalized high-risk cardiovascular（CV） patients.Methods Five thousand two hundred and fifty-four patients over 50 years old at high CV risk were involved in the study.Peripheral arterial disease（PAD） was defined as an ankle brachial index（ABI）0.9 in either leg.They were divided into 6 clinical subgroups： PAD group,coronary heart disease（CHD） group,ischemic stroke（IS） group,diabetes mellitus（DM） group,PAD and CHD or IS or DM,control group.Analyses were performed to compare medication use in all patients.Results Among 5254 patients,65.4%,36.9%,and 46.9% patients received antiplatelet agent,statins and ACEI respectively.Antiplatelet,statins,or ACEI alone and combination of 3 medications were used less frequently in PAD group than in CHD group.Coadministration of the 3 drugs was seen only 56% CHD,8% stroke,13% DM 21% PAD patients.Conclusion PAD is less effective than CHD.All manifestations of atherosclerosis deserve optimal treatment

关 键 词：动脉粥样硬化 踝臂指数 治疗情况 

分 类 号：R543.5[医药卫生—心血管疾病]