2-戊基蒽醌的合成研究  

Synthesis of 2-Amylanthraquinone

作　　者：于海涛[1] 康汝洪[1] 董玉环[2] 朱智甲[1] 甄小丽[3] 韩建荣[1] 

机构地区：[1]河北师范大学化学系,河北石家庄050016 [2]唐山师范专科学校化学系,河北唐山063000 [3]河北科技大学基础部,河北石家庄050018

出　　处：《精细化工》2000年第2期106-108,共3页Fine Chemicals

基　　金：河北省教委基金!资助项目(96221)

摘　　要：首次以苯和叔戊醇为基础原料经烷基化、酰基化和关环３ 步反应合成了２戊基蒽醌。改进和优化了各步合成工艺条件：在三氯化铝－ 硫酸双酸催化下，当ｎ（ＡｌＣｌ３）∶ｎ（Ｈ２ＳＯ４）＝ １∶１－２５，ｎ（Ｃ６Ｈ６）∶ｎ（ｔＣ５Ｈ１１ＯＨ） ＝９∶１，温度６ ℃，反应４ ｈ 时，戊苯收率为７９－３％ ；在２甲基吡啶存在下，中间体２（４′戊基苯甲酰） 苯甲酸收率为８０－２ ％ ；关环反应采用氯仿为溶剂，利用类似分水器的装置，有效控制反应温度使炭化减少，２戊基蒽醌收率为８１－４ ％ 。Using benzene and tert amyl alcohol as starting materials,a new method for preparation of 2 amylanthraquinone involving Friedel Crafts alkylation,acylation and cyclization was described.In the presence of AlCl\-3 and H\-2SO\-4 catalysts,when the molar ratio of AlCl\-3∶H\-2SO\-4 was 1∶1 25,and C 6H 6∶t C 5H 11 OH was 9∶1, reaction holding at 6 ℃ for 4 h,amylbenzene was obtained in 79 3% yield.In the presence of 2 methylpyridine,the intermediate product 2 (4′ amylbenzoyl)benzoic acid was formed in 80 2% yield. By use of a device similar to water segregator and by controlling the temperature,cyclization of the intermediate product in chloroform reduced carbonization and gave 2 amylanthraquinone in 81.4% yield.

关 键 词：叔戊醇 戊基蒽醌 苯酐 合成 

分 类 号：TQ244.63[化学工程—有机化工]