小剂量多巴酚丁胺心电图负荷试验与超声心动图负荷试验在冠心病诊断中的临床对比分析  

The comparison analysis of low-dose dobutamine electrocardiography stress test and echocardiography stress test in the diagnosis of coronary artery disease

作　　者：王刚强[1] 

机构地区：[1]河南省商丘市第一人民医院超声科,476100

出　　处：《中国医师进修杂志》2012年第4期16-18,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的对比分析小剂量多巴酚丁胺心电图负荷试验与超声心动图负荷试验在冠心病诊断中的临床应用价值。方法选择拟诊为冠心病患者56例，分别行小剂量多巴酚丁胺心电图负荷试验和超声心动图负荷试验，并与冠状动脉造影检查结果进行比较，计算小剂量多巴酚丁胺心电图负荷试验和超声心动图负荷试验的敏感度、特异度和准确度。结果56例患者均完成3项检查，冠状动脉造影显示37例患者存在冠状动脉狭窄。小剂量多巴酚丁胺心电图负荷试验诊断冠心病的敏感度、特异度和准确度分别为62．16％（23／37）、73．68％（14／19）和66．07％（37／56），超声心动图负荷试验的敏感度、特异度和准确度分别为86．49％（32／37）、52．63％（10／19）和75．00％（42／56），两种检查方法的敏感度、特异度比较差异有统计学意义（P〈0．05）。结论在冠心病的诊断中，小剂量多巴酚丁胺心电图负荷试验具有较高的特异度，超声心动图负荷试验具有较高的敏感度和准确度，两者联合应用具有较高的临床应用价值。Objective To compare low-dose dobutamine electrocardiography （ECG） stress test and echocardiogTaphy （ECHO） stress test in the diagnosis of coronary artery disease （CHD）. Methods Fifty-six patients with CHD were chosen. They were given dobutamine before test in the speed of 1 μg/（kg·min ）, and gradually increased to 5 μg/（kg·min ）. Low-dose dobutamine ECG stress test, ECHO stress test and coronary angiography （CAG） were performed, and the results were compared. The sensitivity, specificity and accuracy of low-dose dobutamine ECG stress test and ECHO stress test were calculated. Results CAG showed 37 cases of patients with coronary artery stenosis. The sensitivity,specificity and accuracy of low-dose dobutamine ECG stress test were 62.16% （23/37）, 73.68% （14/19） and 66.07% （37/56）. The sensitivity, specificity and accuracy of ECHO stress test were 86.49% （32/37）,52.63% （10/19） and 75.00% （42/56）. There were significant differences in sensitivity and specificity between two test methods （P 〈0.05）. Conclusions In the diagnosis of CHD, low-dose dobutamine ECG stress test has high specificity,and ECHO stress test has high sensitivity and accuracy. Combination of them has high clinical value.

关 键 词：多巴酚丁胺 心电描记术 超声心动描记术 冠状动脉疾病 

分 类 号：R541.4[医药卫生—心血管疾病]