负荷超声心动图与负荷单光子发射计算机断层显像评价冠脉介入术后再狭窄(英文)  

Evaluation of restenosis after PCI with stress echocardiography and stress SPECT

作　　者：常超[1] 信栓力[1] 朱元州[2] 李玉玲[1] 赵秀峰[1] 贾秀萍 李琴[1] 

机构地区：[1]邯郸市第一医院心内科邯郸市心血管病研究所,河北邯郸056002 [2]武汉科技大学附属天佑医院重症医学科 [3]邯郸市职工疗养院内科

出　　处：《心血管康复医学杂志》2012年第1期47-50,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：河北省卫生厅重点项目课题(07150)~~

摘　　要：目的:探讨运用多巴酚丁胺负荷超声心动图(DSE)和硝酸甘油负荷单光子发射计算机断层灌注显像(SPECT)来评价经皮冠状动脉介入(PCI)术后再狭窄的价值。方法:39例PCI术后的患者,在冠状动脉造影前1周内接受DSE和SPECT检查,多巴酚丁胺剂量递增方案为5μg.kg-1.min-1,10μg.kg-1.min-1,20μg.kg-1.min-1,30μg.kg-1.min-1,40μg.kg-1.min-1五个级别,每级负荷维持3min。按照冠脉造影的结果确定DSE,SPECT的敏感性、特异性和准确度,分析比较DSE,SPECT和冠脉造影检查的结果。结果:与冠脉造影相比,SPECT、DSE检查评价PCI术后再狭窄的敏感性(83.3%比75.0%),准确性(71.8%比87.2%)无显著差异P>0.05,但与SPECT相比,DSE检查的特异性较高(66.7%比92.6%),P<0.05。结论:多巴酚丁胺负荷超声心动图评价经皮冠状动脉介入术后再狭窄准确,且特异性好于SPECT。Objective：To study clinical application value of dobutamine stress echocardiography（DSE） and nitroglycerin stress single photon emission computed tomography（SPECT） for evaluation of restenosis after percutaneous coronary intervention（PCI）.Methods：A total of 39 patients after PCI were examined by DSE and SPECT one week before coronary angiography（CAG）.Dose incremental program of dobutamine included five levels：5μg·kg-1·min-1,10μg·kg-1· min-1,20μg·kg-1·min-1,30μg·kg-1·min-1,40μg·kg-1·min-1,and each level maintained for three minutes.Sensitivity,specificity and accuracy of DSE and SPECT were determined according to CAG examined result and examined results were compared between DSE and SPECT.Results：Compared with CAG,SPECT and DSE were no significant differences（P〉0.05）in sensitivity（83.3% vs.75.0%） and accuracy（71.8% vs.87.2%） for evaluating restenosis after PCI,but compared with SPECT,DSE possessed higher specificity（66.7% vs.92.6%）.Conclusions：Dobutamine stress echocardiography is accurate,and its specificity is better than that of SPECT for evaluating restenosis after percutaneous coronary intervention.

关 键 词：多巴酚丁胺 超声心动描记术 压力 体层摄影术 发射型计算机 单光子 冠状动脉再狭窄 

分 类 号：R541.409[医药卫生—心血管疾病]