植物DNA甲基化研究进展  

Research Advances in DNA Methylation of Plant

作　　者：张莉[1] 贾峰[1] 张广乐[1] 曾磊[1] 伊艳杰[1] 王金水[1] 

机构地区：[1]河南工业大学生物工程学院,河南郑州450001

出　　处：《安徽农业科学》2012年第6期3218-3221,共4页Journal of Anhui Agricultural Sciences

基　　金：河南工业大学博士科研基金项目(2011BS031)

摘　　要：[目的]概述植物DNA甲基化的研究进展。[方法]综述了植物DNA甲基转移酶s、iRNA指导的DNA甲基化过程,阐明了DNA甲基化与其他表观遗传修饰的关系。[结果]DNA甲基化在表观遗传控制体系中起着重要作用,维持着生物进化过程中基因组和表观遗传的稳定性。RNA介导的DNA甲基化作用中s,iRNA起着不可替代的作用,但RdDM和甲基化在基因调控中的作用需要更进一步研究。[结论]全面了解DNA甲基化及其在植物发育和逆境胁迫应答中的作用,可以在转录水平上增强或抑制外源基因和内源基因沉默,便于制定更合理的改良重要转基因作物的策略。[Objective] To review the research advances in DNA methylation of plants.[Method] The DNA methyltransferase and siRNA-guided DNA methylation process was reviewed and the relation between DNA methylation and other epigenetic modification was expounded.[Result] DNA methylation played an important role in the epigenetic control system,it maintained the stability of genome and epigenetic modification in organic evolution process.siRNA played an irreplaceable role in RNA-mediated DNA methylation process,but the role of RdDM and methylation in gene regulation still needed further research.[Conclusion] The study gave a comprehensive summary of DNA methylation and its role in plant growth and response to adverse stress,which could enhance or inhibit epigenetic and endogenous gene silencing at the transcript level,so as to better improve the important transgenic crops.

关 键 词：DNA甲基化 表观遗传 RDDM 

分 类 号：Q943.2[生物学—植物学]