非糖尿病急性心肌梗死患者入院时血糖与冠状动脉病变及左心功能的关系  

Association of hyperglycemia on admission with severity of coronary artery disease and left ventricular function in tients with acute myocardial infarction

作　　者：徐远胜[1] 许国根[1] 章浩[1] 

机构地区：[1]杭州市第一人民医院急诊科,310006

出　　处：《浙江医学》2012年第1期36-38,共3页Zhejiang Medical Journal

摘　　要：目的探讨非糖尿病患者入院时血糖与急性心肌梗死（AMI）冠状动脉病变程度及左心功能的关系。方法根据入院时血糖水平将180例经皮冠状动脉介入治疗（PCI）的无糖尿病史的AMI患者分为观察组（85例，血糖≥7．8mmol／L）和对照组（95例，血糖〈7．8mmol／L）。对两组的冠脉造影结果及左室射血分数（LVEF）、肌酸激酶（CK）峰值和住院时间进行比较分析。结果两组患者单支血管病变分布的差异无统计学意义（P〉0．05），观察组发生多支血管病变的患者明显多于对照组，差异有统计学意义（P〈0．05）。观察组CK峰值明显高于对照组，LVEF显著低于对照组，差异均有统计学意义（P〈0．05或0．01）。结论非糖尿病AMI合并入院时高血糖提示多支血管病变和左心功能减退。Objective To investigate the association of hyperglycemia on admission with the severity of coronary artery disease and left ventricular function in acute myocardial infarction of non-diabetic patients. Methods One hundred and eighty non-diabetic patients with acute myocardial infarction （AMI） treated with PCI were divided into control group （〈7.8mmol/l） and observation group （≥ 7.8mmol/I） according to the blood glucose level on admission. The coronary angiography findings, LVEF, maximum CK and mean time of hospitalization were compared between two groups. Results Patients with hyperglycemia had more prevalence of multivessel coronary disease（P〈0.05）, higher maximum CK（P〈0.05） and lower LVEF（P〈0.01） than patients without hyperglycemia, there were no significant differences in infarction-related artery and mean time of hospitalization between two groups. Conclusion Hyperglycemia in non-diabetic AM I patients may suggest multivessel coronary disease and left ventricular hypofunction.

关 键 词：高血糖 心肌梗死 冠状动脉疾病 

分 类 号：R541.4[医药卫生—心血管疾病]