Studies on the synthesis,pungency and anti-biofouling performance of capsaicin analogues  

作　　者：PENG BiXian WANG JunLian PENG ZhengHong ZHOU ShengZe WANG FengQi JI YongLiang YE ZhangJi ZHOU XiangFeng LIN Tong ZHANG XiaoBin 

机构地区：[1]Technical Institute of Physics and Chemistry,Chinese Academy of Sciences,Beijing 100190,China [2]State Key Laboratory of Silicon Materials,Department of Materials Science and Engineering Zhejiang University,Hangzhou 310027,China [3]Beijing TianLongYaYuan International Biology Company of High and New Science and Technology,Beijing 102209 [4]Beijing JiuZhouLongLing Company of Advanced Materials for Environmental Protection,Beijing 102209,China [5]Guangdong Shantou MingHong Chemicals Company Ltd,Shantou 515041 [6]Ship Coating Testing Station of China Ship Industrial Xiamen,Xiamen 361002,China [7]Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190,China [8]School of Engineer Technology,Deakin University,Geelong Victoria 3217,Australia

出　　处：《Science China Chemistry》2012年第3期435-442,共8页中国科学（化学英文版）

基　　金：supported by the National HighTechnology Research and Development Program of China (863 Program 2010AA065104)

摘　　要：Ten capsaicin analogues were synthesized and their pungency degrees were determined through Scoville Organoleptic Test. The relationship between the structure and pungency degree of these capsaicin analogues was discussed. Then four of these capsaicin analogues with higher pungency degree were picked out and added to anti-biofouling paints as repellents to study their anti-biofouling performance by shallow sea buoyant raft hung-plate experimentation. The results showed that capsaicin and dihydrocapsaicin exhibited equally good anti-biofouling performance while nordihydrocapsaicin and N-vanillylnonanamide had poor anti-biofouling performance. Experimental results also showed that the paints with only 0.1% capsaicin or dihydrocapsaicin as repellent without any other biocides had also exhibited good anti-biofouling performance, which provided a new idea for developing novel, more environment-friendly and Cu20-free antifouling paints.Ten capsaicin analogues were synthesized and their pungency degrees were determined through Scoville Organoleptic Test.The relationship between the structure and pungency degree of these capsaicin analogues was discussed.Then four of these capsaicin analogues with higher pungency degree were picked out and added to anti-biofouling paints as repellents to study their anti-biofouling performance by shallow sea buoyant raft hung-plate experimentation.The results showed that capsaicin and dihydrocapsaicin exhibited equally good anti-biofouling performance while nordihydrocapsaicin and N-vanillylnonanamide had poor anti-biofouling performance.Experimental results also showed that the paints with only 0.1% capsaicin or dihydrocapsaicin as repellent without any other biocides had also exhibited good anti-biofouling performance,which provided a new idea for developing novel,more environment-friendly and Cu2O-free antifouling paints.

关 键 词：capsaicin analogues PUNGENCY relationship between structure and pungency degree anti-biofouling performance 

分 类 号：TQ637.2[化学工程—精细化工] TU603[建筑科学—建筑技术科学]