保山市2轮麻疹疫苗强化免疫情况及效果评价  

Evaluation on effect of the two round supplementary immunization of measles vaccine in Baoshan of Yunnan province

作　　者：张安柱[1] 郑维斌[1] 张腾[1] 段生朝[1] 林冬梅[1] 马崇惠[1] 王黎明[1] 段平常[1] 

机构地区：[1]保山市疾病预防控制中心,云南保山678000

出　　处：《中国预防医学杂志》2012年第2期143-146,共4页Chinese Preventive Medicine

摘　　要：目的对保山市2轮麻疹疫苗(MV)强化免疫情况及效果进行分析,为该市尽早消除麻疹提供科学的依据。方法利用保山市2008、2010年麻疹疫苗强化免疫报告、调查接种率,麻疹发病情况,2009、2010年麻疹IgG抗体水平调查和法定麻疹报告系统资料进行统计学描述,SPSS 11.5进行统计学分析,率之间的比较用卡方检验,并用趋势检验对麻疹发病率、抗体阳性率趋势变化进行分析,检验水准均为α=0.05,P<0.05为差异有统计学意义。结果保山市强化免疫报告、调查接种率均在98%以上;2轮强化免疫后,麻疹IgG抗体水平较第1轮强化免疫后得到明显提高(χ2=55.943,P<0.001),人群抗体阳性率达95.02%,且随着年龄段的增长,抗体阳性率无变化(rs=0.500,P>0.05);同时,麻疹发病率由2007、2008年的平均发病率5.99/10万下降至2009年的1.08/10万、2010年的0.12/10万,发病率分别下降了81.97%、98.00%,2010年8月至2011年9月无麻疹病例报告。结论 2轮强化免疫后,保山市麻疹疫情得到有效控制,为该市尽早消除麻疹奠定了坚实基础。Objective To evaluate effect of two round supplementary immunization of measles vaccine in Baoshan of Yunnan province.Methods Descriptive analysis was made according to the vaccination rate of measles vaccine for supplementary immunization.Data were obtained from the field investigation and the legal measles epidemic reporting system,and detection of antibody levels.Results The two round vaccination rate of measles vaccine was all above 98%.At the same time,the antibody level of measles was greatly improved to 95.02%（P0.001）and the incidence of measles greatly decreased from 5.99/100000 to 1.08/100000 of 2009 and 0.12/100000 of 2010,finally there was no measles cases which had been reported so far.Conclusions The incidence of measles was effectively controlled after two round supplementary immunization of measles vaccine.

关 键 词：麻疹疫苗 强化免疫 效果评价 

分 类 号：R186[医药卫生—流行病学]