结合硬斑块特征的心血管内超声图像中-外膜边缘检测  

Hard Plaque Characteristics Based Media-Adventitia Border Detection in Intravascular Ultrasound Images

作　　者：邢栋[1] 杨丰[1] 黄靖[1] 涂圣贤[2] DIJKSTRA Jouke 

机构地区：[1]南方医科大学生物医学工程学院,广州510515 [2]莱顿大学医学中心放射科,荷兰莱顿

出　　处：《中国生物医学工程学报》2012年第1期25-31,共7页Chinese Journal of Biomedical Engineering

基　　金：国家自然科学青年基金(81000642);国家自然科学基金(60672115)

摘　　要：针对心血管内超声(IVUS)图像中-外膜(media-adventitia)边缘检测中,硬斑块和声影等造成中-外膜边缘难以准确检测的问题,提出一种结合硬斑块特征的中-外膜边缘检测方法。首先,采用k均值聚类分割IVUS图像,根据图像中不同类型斑块的成像特点检测硬斑块位置;然后,计算IVUS图像方向梯度,结合斑块位置和图像灰度,获得代价矩阵;最后,利用启发式图搜索方法,实现IVUS图像的中-外膜边缘检测。对临床图像的实验结果表明,本方法能克服图像中声影和斑块干扰等问题,使检测正确率达到95.57%,提高了IVUS图像中-外膜边缘检测的准确性。This paper presents a new approach for the detection of media-adventitia border in intravascular ultrasound（IVUS） images,to overcome problems of hard plaque and acoustic shadow which make media-adventitia difficult to detect.The approach started with image classification using k-means algorithm,such that the region of hard plaques was delineated from the IVUS image.In a next step,a cost matrix was created by combining image gradient,hard plaque location and image intensity.A heuristic graph-searching was then applied to find the media-adventitia border from the cost matrix.Experiment results showed that the approach improved the accuracy of media-adventitia border detection by overcoming problems caused by acoustic shadow and hard plaque inhomogeneity,and the correct rate reached 95.57%.

关 键 词：心血管内超声 中-外膜边缘 硬斑块 启发式图搜索 

分 类 号：R318[医药卫生—生物医学工程]