运动平板试验评估曲美他嗪治疗稳定型心绞痛的疗效观察  

Effectiveness of Trimetazidine on Stable Angina Evaluated by Treadmill Exercise Test

作　　者：戴红艳[1] 何涛[1] 姜陆民[1] 丁华民[1] 

机构地区：[1]青岛市市立医院心内科,山东青岛266011

出　　处：《中国医疗设备》2012年第2期118-119,61,共3页China Medical Devices

摘　　要：目的通过运动平板试验(Treadmill Exercise Test,TET)观察曲美他嗪辅助治疗稳定型心绞痛的疗效。方法选取80例明确诊断为稳定型心绞痛且运动平板试验为阳性患者,在传统药物治疗基础上,分为曲美他嗪治疗组及对照组。记录治疗前后运动平板试验阳性率、运动终止时诱发心绞痛率、运动时间、恢复时间、运动后2min ST段压低≥1.0mm的导联数及其ST段压低总和(∑ST),并进行统计分析。结果曲美他嗪治疗后运动平板试验阳性率、运动终止时诱发心绞痛率、运动时间、恢复时间、运动后2minST段压低≥1.0mm的导联数及其ST段压低总和(∑ST)较治疗前及对照组均有显著改善,且差异具有统计学意义(P<0.05)。结论在传统药物治疗基础上联用曲美他嗪,可使稳定型心绞痛患者进一步获益。Objective Tn evaluate the effectiveness of trimetazidi/ne on stable angina by treadmill exercise test （TET）. Methods 80 TET positive patients with stable angina were divided into 2 groups： the trimetazidine group and the control group. Before and after therapy, the positive rate, exerciseinduced angina rate at the termination, exercise time, recovery time, the number of leads with ST-segment depression〉 1.Omm 2 minutes after exercise and the sum of ST-segment depression（EST） were recorded and analyzed. Results After therapy with Trimetazidine, the positive rate, exercise-induced angina rate at the termination, exercise time, recovery time, the number of leads with ST-segment depression〉 1.0mm 2 minutes after exercise and the sum of ST-segment depression（Е,ST） were all improved apparently compared with control group（P〈O.05）. Conclusion Patients with stable angina could benefit from the combined treatment with Trimetazidine on the basis of the traditional drug therapy.

关 键 词：曲美他嗪 稳定型心绞痛 运动平板试验 

分 类 号：R541.4[医药卫生—心血管疾病]