姝乐颗粒剂制备工艺的研究及定性分析  

The preparation technique and qualitative analysis of ShuLe granules

作　　者：景莉[1] 孙伟张[1] 张丽[2] 曹卫[1] 

机构地区：[1]成都军区总医院药学部,成都610083 [2]贵阳医学院药学系,95级贵阳550004

出　　处：《药学实践杂志》2000年第1期21-24,共4页Journal of Pharmaceutical Practice

摘　　要：目的:研究中药姝乐颗粒制的制备工艺及定性鉴别。方法:利用正交实验设计优化提取条件,以收膏率为指标,采用二因素(煎煮时间和加水量倍数),三水平进行煎煮条件的选择。并采用薄层色谱法对制剂中川芎,当归,延胡索进行了定性鉴别。结果:优选出的煎煮条件为A1B1,即第一次加15倍量水煎煮15h,第二次加10倍量水煎煮10h。且薄层色谱斑点清晰。结论:本提取工艺及质量可行。OBJECTIVE:To study the preparation technique and qualitative identification of ShuLe granules(preparation of chinese medicine).METHODS:The optimal extractive factors were found with orthogonal experiment design with table L 9(3 4),the index were the extraction recovery rate.Thin-layer chromatography was employed for qualitative identification of the herbs of Ligusticum Chuanxiog Hort, Angelica Sinensis (Oliv)and Corydalis Turtschaninovii Bess.RESULTS:The optimal extract technique was boiling two times,the first boiling 1.5h,adding 15 times content water,the second boiling 1.0h,adding 10 times content water,and definition of the sports was good.CONCLUSION:The extraction technique and the quality standards are feasible.

关 键 词：姝乐颗粒剂 正交设计 薄层层析法 中药 

分 类 号：R283.627[医药卫生—中药学]