贵阳城区健康成人男性维生素D营养状况调查  被引量:10

Survey of vitamin D status in 700 healthy adult males in Guiyang, China

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作  者:张巧[1] 时立新[1] 彭年春[1] 庄惠君[1] 吴丹荣[1] 张景璐[1] 

机构地区:[1]贵阳医学院附属医院内分泌代谢病科,550004

出  处:《中华医学杂志》2012年第6期397-400,共4页National Medical Journal of China

基  金:贵州省优秀科技教育人才省长专项资金项目[黔省专合字(201082)]

摘  要:目的了解贵阳城区健康成人男性维生素D营养状况。方法抽取贵阳市主城区一社区,在该社区中按年龄段进行分层抽样,抽取20-79岁健康成人男性700名。2009年11月至2010年1月进行问卷调查,同时采集清晨空腹静脉血,分离血清测定血清25.羟维生素D[25(OH)D]水平。结果资料齐全的627名贵阳城区健康成人男性血清25(OH)D水平为(214-10)肛g/L;维生素D缺乏[25(OH)D〈μg/L]、不足[20斗∥L≤25(OH)D〈30μg/L]及正常者[25(OH)D≥30μg/L]分别为315例(50.2%)、202例(32.2%)及110例(17.6%);青年(20-39岁)、中年(40~59岁)及老年(60~79岁)组血清25(OH)D水平正常者分别为72、152、105例,血清25(OH)D水平依次为(18±10)斗g/L、(24±10)斗g/L及(22±8)μg/L;不吸烟组较吸烟组具有更高25(OH)D水平(22斗g/L比μg∥L,P=0.003);调查对象中受教育年限≤6年、7-9年、10~12年及≥13年组血清25(OH)D水平分别为(24±10)μg/L、(23±10)μg/L、(22±9)μg/L及(18±9)μg/L,25(OH)D水平与受教育年限呈负相关(r=-0.138,P=0.000)。结论贵阳城区健康成人男性维生素D缺乏现象普遍,尤其见于青年人、吸烟及高学历者。Objective To evaluate the vitamin D status of healthy adult males living in Guiyang. Methods A total of 700 healthy volunteers aged 20 -79 years were selected randomly from a community in Guiyang by stratified sampling method. Questionnaires for living habits and fasting blood samples were collected in the morning from November 2009 to January 2010. The serum concentrations of 25-hydroxyvitamin D were measured by the DiaSorin radioimmunoassay kit. Results The mean levels of serum 25(OH)D was (21 ± 10) txg/L. And the percentages of vitamin D deficiency (25(OH)D 〈20 Ixg/L), insufficiency (20 I.Lg/L〈25 (OH) D 〈 30 ixg/L) and sufficiency (25 (OH) D 230. 0 μg/L) were 315 (50. 2% ), 202( 32. 2% ) and 110( 17. 6% )respectively. The concentrations of serum 25 (OH)D in young, middle-aged and old adults were (18±10) μg/L, (24 ± 10) μg/L and (22 ± 8 )μg/L respectively. The serum level of 25(OH)D was lower in the smokers than that in the non-smokers(20 μg/L vs 22 μg/L, P = 0. 003 ). The serum concentrations of 25 (OH) D were (24 ±10) Ixg/L , (23 + 10) Ixg/L, (22 + 9 ) μg/L and (18 + 9) μg/L in education level ( ≤6, 7 - 9, 10 - 12 and ≥ 10 years in school) respectively. Significant inverse correlations existed between the concentrations of serum 25 (OH) D and the education levels (r = -0. 138, P = 0. 000). Conclusion The prevalence of hypovitaminosis D is common in healthy adult males in Guiyang, especially among the youth, smokers and higher educated groups.

关 键 词:流行病学 成年人 25-羟维生素D 

分 类 号:R725.914.4[医药卫生—儿科]

 

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