电针中极穴对膀胱逼尿肌功能的调节作用  

Regulatory Effect of Electroacupuncture at Zhongji on Detrusor Function of Bladder

作　　者：韩静[1] 叶笑然[1] 孟宪军[2] 陈玄[1] 黄晓卿[1] 

机构地区：[1]福建省中医药研究院,福建福州350003 [2]厦门大学医学院中医系,福建厦门361005

出　　处：《福建中医药大学学报》2012年第1期6-9,共4页Journal of Fujian College of Traditional Chinese Medicine

基　　金：福建省自然科学基金资助课题(2009J05070);福建省卫生厅青年科研课题(2009-1-39);福建省卫生厅中医药重点课题(WZ-ZQ0902)

摘　　要：目的从尿动力学角度阐明电针中极穴对膀胱逼尿肌功能亢进和减弱2种异常状态的调节作用。方法雄性新西兰兔100只,以新斯的明制作膀胱逼尿肌功能亢进模型,以东莨菪碱制作膀胱逼尿肌功能减弱模型,在2种模型上电针中极穴,刺激频率为2 Hz和100 Hz,观察电针干预下尿动力学指标的动态变化,检测记录电针期间膀胱内压波型分型及电针结束即刻的尿液排出速度。结果电针2 Hz组可显著减慢膀胱逼尿肌功能亢进模型增快的排尿速度,电针2 Hz、100 Hz均可显著加快膀胱逼尿肌功能减弱模型减慢的排尿速度。结论电针中极穴可调节膀胱排尿期逼尿肌功能异常,电针作用存在频率差异性,电针2 Hz组比100 Hz组作用大。Objective To explore the regulatory effect of electroacupuncture at Zhongji （CV3） on hyperfunction and function inhibition of detrusor based on the urodynamic study. Methods 100 male New Zealand Rabbits were selected as trial objects. The model of detrusor hyperfunction was produced by neostigmine, and model of function inhibition of detrusor was produced by anisodamine. Electroacupuncture at CV3 was practised on both models, and the frequency of stimulation was 2 Hz, 100 Hz respectively. The dynamic changes of urodynamic index were observed, and the wave pattern of intravesical pressure during electroacupuncture and urination flow rate after electroacupuncture were recorded. Results Electroacupuncture at CV3 with 2 Hz frequency decreased the increasing urination flow rate produced by neostigmine. Electroacupuncture at CV3 with the two kinds of frequency accelerated the slowed urination flow rate produced by anisodamine. Conclusion Electroacupuncture at CV3 can regulate detrusor dysfunction during voiding, and the effect is related with the frequency of electroacupuncture. Electroacupuncture with 2 Hz frequency has better effect than that with 100 Hz frequency.

关 键 词：电针 中极 膀胱 尿动力学 逼尿肌功能亢进 逼尿肌功能减弱 

分 类 号：R246.2[医药卫生—针灸推拿学]