青礞石FTIR指纹图谱研究  

Fingerprints of Chloriti Lapis by FTIR

作　　者：刘圣金[1] 吴德康[1] 林瑞超[2] 刘训红[1] 傅兴圣[1] 孔庆友[3] 安书芳 

机构地区：[1]南京中医药大学,江苏南京210046 [2]中国药品生物制品检定所,北京100050 [3]南京大学,江苏南京210093 [4]河北灵寿县华源云母厂,河北灵寿050500

出　　处：《中成药》2012年第2期191-195,共5页Chinese Traditional Patent Medicine

基　　金：国家十一五科技支撑计划项目(2006BAI55B02);江苏省普通高校研究生创新计划项目(CX09B-282Z);江苏省名老中医药专家师承项目(2009)

摘　　要：目的建立青礞石的傅利叶变换红外光谱指纹图谱,并分析比较青礞石炮制前后图谱变化。方法通过傅利叶变换红外光谱仪对不同产地和批次10份青礞石样品进行分析,相似度评价以计算共有峰透光率的夹角余弦值获得。结果青礞石样品的指纹图谱相似度均大于0.96;青礞石炮制后相似度和相关系数均有较大程度的降低。结论傅利叶变换红外光谱指纹图谱可用于青礞石炮制后的品质评价。AIM To establish the fingerprints of Chloriti Lapis by FTIR,and to compare their fingerprints between samples processed and the crude ones.METHODS With the use of FTIR,ten batches of Chloriti Lapis samples from different prodution areas were analyzed and the angle cosine value of transmittance（%） of common peaks were calculated to get similarity of fingerprint.RESULTS The experiment showed that all the similarities of the samples were more than 0.96.The similarities and the correlation coefficients of the processed samples revealed a significant decrease.CONCLUSION The FTIR fingerprint could be used for evaluation of the processing quality of Chloriti Lapis commodities.

关 键 词：青礞石 傅利叶变换红外光谱 指纹图谱 

分 类 号：R284.1[医药卫生—中药学]