柴藿颗粒制粒工艺的研究  

The Research on Granulating Technology for Granules of Bupleurum and Agastache

作　　者：阳敬[1] 李姝梅[1] 熊磊[1] 韦静[1] 高文全[1] 李安华[1] 

机构地区：[1]云南中医学院,云南昆明650500

出　　处：《云南中医学院学报》2012年第1期13-15,共3页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：云南省教育厅科学研究基金重大项目

摘　　要：目的:优选柴藿颗粒的最佳制剂工艺。方法:按L9(34)进行考察的最佳成型工艺,即药粉与辅料比,糖粉与糊精比,润湿剂(乙醇)浓度3个因素,以成品率及流动性为指标进行综合评价,筛选出最佳成型工艺参数。结果:以药粉:辅料为1∶1.5,糊精:糖粉1∶5,乙醇浓度为70%为水提浸膏粉颗粒成型最佳条件。结论:柴藿颗粒制粒工艺条件的筛选,方法简便,稳定可控,为中试工艺的生产提供了科学理论依据。Objective： To select the optimum preparatio Agastache. Methods： The optimum preparation technology examined proportion of powder and auxiliary materials, proporation of powdere n technology for granules of Bupleurum and by L9 （34） refer to the synthetic process that d sugar and dextrin, and adhesive used as de- tected factors and the mobility as detected index, which aim to find the best preparation of parameters. Result ： The proportion of powder and auxiliary materials was 1 ： 1.5, proportion of dextrin and powdered sugar was 1 ： 5, and optimum preparation technology of experiment, which were the best conditions of optimum preparation technology found in this experiment. Conclusion： This preparation technology made in this research was convenient, steady and controllable, which provided pilot process with scientific basis.

关 键 词：柴藿颗粒 正交试验 制粒工艺 

分 类 号：R285.6[医药卫生—中药学]