妊娠期和哺乳期女性免疫抑制药的使用  

Use of immunosuppressive agents in pregnancy and lactation women

作　　者：孙闻嘉[1] 薛静[1] 吴华香[1] 

机构地区：[1]浙江大学医学院附属第二医院风湿免疫科,杭州市310009

出　　处：《临床药物治疗杂志》2012年第1期56-62,共7页Clinical Medication Journal

摘　　要：妊娠期和哺乳期女性是多种炎症疾病的高发人群,如类风湿关节炎、系统性红斑狼疮、炎性肠病等。目前治疗炎症疾病的主要药物包括糖皮质激素、免疫抑制药以及近年来迅速发展的生物制剂。但是关于这类药物用于妊娠期及哺乳期女性的利弊,通常是经验性的,多数缺乏随机对照研究。本文在回顾文献的基础上对妊娠及哺乳期女性激素及免疫抑制药使用的相关内容进行了综述。WOmen of pregnancy and lactation are often involved in inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus and other rheumatic diseases. Glucocorticoids, immunosuppressive agents and biologic agents which have developed greatly in recent years are frequently used to treat the inflammation. However knowledge of the risks and benefits of treating women with these drugs during pregnancy and lactation periods is usually empirical and is lack of evidence from randomized clinical trials. Here we try to discuss the usage of immunosuppressive agents in pregnancy and lactation based on literature reviews.

关 键 词：妊娠期 哺乳期 激素 免疫抑制药 生物制剂 炎症疾病 

分 类 号：R714.1[医药卫生—妇产科学] R971.1[医药卫生—临床医学]