药物成瘾者生命质量测定量表在美沙酮维持治疗病人中的应用  

Application of the scale of quality of life for drug addicts(QOL-DA) receiving methadone maintenance treatment(MMT)

作　　者：罗莉[1] 刘普林[1] 丁洁[1] 石萍 尹平[3] 姚中兆[1] 周旺[1] 

机构地区：[1]武汉市疾病预防控制中心,武汉430015 [2]武汉市皮肤病性病防治所,武汉430078 [3]华中科技大学同济医学院流行病与卫生统计教研室,武汉430078

出　　处：《中国艾滋病性病》2012年第1期30-32,共3页Chinese Journal of Aids & STD

基　　金：武汉市卫生局科研项目(WG08B03)~~

摘　　要：目的对药物成瘾者生命质量测定量表(QOL-DA)在美沙酮维持治疗病人中应用的信度、效度和反应度进行检验。方法采用分层随机抽样的方法,调查293名美沙酮社区维持治疗门诊病人和109名社区海洛因成瘾者,采用内部一致性可信度和分半信度进行信度检验,结构效度和区分效度采用因子分析、相关分析、t检验。结果总量表及各维度Cronbach’sα系数在0.7以上,因子分析符合逻辑关系,8个公因子累计方差贡献率达62.99%,四个维度方差贡献率分别为30.221%、13.187%、8.763%、10.821%,不同性别维持治疗病人的生活质量差异有统计学意义(t=2.787,P=0.006),维持治疗病人的生活质量明显高于社区海洛因吸食者(P<0.05)。结论 QOL-DA量表具有较好的信度、效度和反应度,可用于美沙酮社区药物维持治疗病人的生活治疗评价。Objective To test the reliability,validity and responsiveness of the scale of quality of life for drug addicts（QOL-DA） receiving methadone maintenance treatment（MMT）.Methods A total of 293 MMT receivers and 109 heroin users were randomly selected for a questionnaire survey using QOL-DA.The reliability of QOL-DA was assessed by internal consistency reliability and split-half reliability.The validity and responsiveness were assessed by factor analysis and t-test.Results The Cronbach＇s α coefficient was more than 0.7.Factor analysis conformed to logic relation,and the cumulative variance was 62.99%.The respective variances of the four fields were 30.221%,13.187%,8.763% and 10.821%.The quality of life between male and female MMT receivers had significant difference（t=2.787,P=0.006）.The quality of life of MMT receivers was higher than that of heroin users.（P0.05）.Conclusion QOL-DA has good reliability,validity and responsiveness,and could be applied to assess MMT receivers＇ quality of life.

关 键 词：药物成瘾者生命质量测定量表 信度 效度 反应度 美沙酮维持治疗病人 

分 类 号：R996[医药卫生—毒理学] R512.91[医药卫生—药学]