反应精馏法催化合成氯乙酸乙酯  

Catalytic synthesis of ethyl chloroacetate by reactive distillation

作　　者：尚会建[1] 赵叶[1] 高攀[1] 康丽娜[1] 王丽梅[1] 王少杰[1] 郑学明[1] 

机构地区：[1]河北科技大学化学与制药工程学院,河北石家庄050018

出　　处：《现代化工》2012年第2期78-81,共4页Modern Chemical Industry

摘　　要：采用反应精馏的方法催化合成了氯乙酸乙酯,反应过程中加入环己烷作为带水剂,将水分带出反应系统后促进酯化平衡朝正向移动。设计了新型的反应器,采用强酸性阳离子交换树脂作为催化剂,催化活性高,且可以循环利用。与其他酯化反应相比,所用无水乙醇量少,反应时间短,转化率高达98.92%。The reactive distillation was used in the catalytic synthesis of ethyl chloroacetate with cyclohexane as the water entrainer to keep the balance moving towards the ester during the reaction. A new reactor is designed and the cation exchange resin is applied as the catalyst due to its hyperactivity and cyclic utilization. Compared with other studies, this method uses smaller amount of raw material and takes shorter reaction time. The total yield can reach up to 98.92%.

关 键 词：氯乙酸 无水乙醇 环己烷 反应精馏 强酸性阳离子交换树脂 

分 类 号：TQ03-39[化学工程]