止呕散穴位贴敷防治顺铂所致消化道反应的临床观察  

The Clinical Observation of Applying Acupoint with Vomitting-arresting Pulvis to Prevent and Treat Gastrointestinal Tract Reaction Caused by Cis-platinum Complexes

作　　者：黄杰[1] 周映伽[1] 沈红梅[1] 

机构地区：[1]昆明医学院第三附属医院云南省肿瘤研究所中西医结合肿瘤临床研究中心,云南昆明650118

出　　处：《昆明医学院学报》2012年第1期48-50,共3页Journal of Kunming Medical College

基　　金：云南省自然科学基金资助项目(2009CD182);云南省教育厅科学研究基金资助项目(2010Y186);云南省卫生厅基金资助项目(2009NS022;2010NS86)

摘　　要：目的探讨止呕散外敷穴位加昂丹司琼与单用昂丹司琼在预防肺癌顺铂化疗后恶心呕吐的效果.方法选取"GP"或"NP"方化疗的非小细胞肺癌共80例,随机分为对照组与治疗组,每组各40例.对照组常规化疗,止吐药选择昂丹司琼;治疗组在对照组基础上,加用由半夏、吴茱萸、生姜等组成的止呕散贴敷患者双侧内关穴、梁门穴和足三里穴,每日更换,21 d为一个观察周期.结果治疗组控制恶心症状有效率为90.0%,完全控制率为57.5%;控制呕吐症状有效率为92.5%,完全控制率为72.5%;对照组控制恶心症状有效率为72.5%,完全控制率为30.0%;控制呕吐症状有效率为77.5%,完全控制率为40.0%;两者差异有统计学意义(P<0.05).结论穴位贴敷治疗可有效防治顺铂所致消化道反应.Objective To compare the effect of applying acupoint with Vomitting-arresting pulvis plus Ondansetron and Ondansetron only to prevent and treat nausea and vomitting caused by cis-platinum complexes in non-small-cell-lung-cancer. Methods 80 non-small-cell-lung-cancer patients treated by ＂GP＂ or ＂NP＂ chemotherapy treatment plan were divided into two groups randomly and averagely： the control group received general chemotherapy treatment, and chose Ondansetron as antemetic. On the base of the control group, the treatment group took Vomitting-arresting pulvis to apply unilateral Neiguan point, Liangmen point and Zusanli point, instead everyday and alternating from left to right. Results In the treatment group, the effective rate of controlling nausea was 90.0%, the complete control rate was 57.5% ; and the effective rate of controlling vomiting was 92.5%, the complete control rate was 72.5%. And in the control group, the effective rate of controlling nause was 72.5%, the complete control rate was 30.0% ; and the effective rate of controlling vomiting was 77.5%, the complete control rate was 40.0%. There was a acupoint with Vomitting-arresting pulvis could cis-platinum complexes. significant difference between two groups. Conclusion effectively prevent and treat gastrointestinal tract reaction Applying caused by

关 键 词：穴位贴敷 顺铂 消化道反应 

分 类 号：R256.3[医药卫生—中医内科学]