8536例健康体检者幽门螺杆菌血清尿素酶抗体阳性率分析  

Analysis on Sero-prevalence of Urease Antibody in Helicobacter pylori Among 8,536 Healthy Examinees

作　　者：陈月梅[1] 王敏[1] 张婷婷[1] 周志芳[1] 蒋洪敏[1] 

机构地区：[1]中南大学湘雅二医院检验科,湖南长沙410011

出　　处：《实用预防医学》2012年第2期254-255,共2页Practical Preventive Medicine

摘　　要：目的了解长沙地区健康体检者幽门螺杆菌血清尿素酶抗体阳性率情况。方法采用胶体金法检测8 536例健康体检者血清幽门螺杆菌尿素酶抗体。结果 8 536例健康体检者幽门螺杆菌血清尿素酶抗体阳性率为25.7%,男女幽门螺杆菌血清尿素酶抗体阳性率经χ2检验差异有统计学意义(P<0.05);各年龄组幽门螺杆菌血清尿素酶抗体阳性率经χ2检验差异亦有统计学意义(P<0.01),但并不随着年龄增大而增加。结论长沙地区幽门螺杆菌的高感染率及其高致病性应引起重视。Objective To study the sero- prevalence of urease antibody in Helicobacter pylori in healthy examinees in Changsha. Methods We detected the urease antibody of Helicobacter pylori in the sera of 8,536 healthy examinees by using colloidal gold method. Results Among 8,536 healthy examinees, the sero- prevalence of urease antibody in Helicobacter pylori was 25.7%. There were statistically significant differences in the seroprevalence of urease antibody in Helicc^cter pylori between males and females by X^2 test （P 〈 0.05）. The sero - prevalence of urease antibody in Helicobacter pylori in different age groups also had statistically significant difference by X^2 test （P 〈 0.01 ）, but the increase of sero- prevalence did not match the increase of ages. Conclusions Close attention should be paid to the prevalence and high pathogenicity of Helicobacter pylori in Changsha.

关 键 词：幽门螺杆菌 尿素酶抗体 胶体金法 

分 类 号：R446.1[医药卫生—诊断学]