围术期应激性高血糖的研究进展  

Progress in studies of perioperative stress hyperglycemia

作　　者：王敬[1] 谭志明[1] 

机构地区：[1]上海复旦大学附属肿瘤医院麻醉科,200032

出　　处：《国际麻醉学与复苏杂志》2012年第3期199-202,共4页International Journal of Anesthesiology and Resuscitation

摘　　要：背景应激性高血糖是机体在严重创伤、危重病、重大手术等应激状态下所产生的一种代谢反应。目前很多研究已经证实围手术期应激性高血糖与临床不良预后有关，是术后并发症和病死率增加的独立危险因素。目的强调积极干预应激性高血糖的必要性和重要性，以及临床医师对于术中发生应激性高血糖患者的处理需要注意的一些问题。内容阐述有关应激性高血糖的最新进展知识包括其发生机制和病理生理改变。趋向临床上对于应激性高血糖患者的治疗逐渐个体化，控制血糖在合理水平以减少术后并发症，改善患者预后。Background Stress hyperglycemia is a common metabolic response to critical illness and severe trauma. It has been demonstrated that perioperative stress hyperglycemia is associated with adverse clinical prognosis and an independent risk factor for postoperative complications and mortality by recent literature. Objective The necessity and importance of intervention in stress hyperglycemia were emphasized. Much attention should be paid to issues in dealing with stress hyperglycemia in clinical work. Content Current knowledge of stress hyperglycemia, including the mechanism and related pathophysiologic changes, are elucidated in this review. Trend The treatment of patients with stress hyperglycemia should be individualized and a reasonable blood glucose level should be get to reduce postoperative complications and improve prognosis.

关 键 词：围术期 应激性高血糖 危重病 麻醉 治疗 

分 类 号：R614[医药卫生—麻醉学]