肝移植围手术期肺部并发症的危险因素及相关防治  

Risk factors of pulmonary complications during the perioperative period of liver transplantation and relevant strategies of prevention

作　　者：许今[1] 王祥瑞[1] 

机构地区：[1]上海交通大学医学院仁济医院麻醉科,200127

出　　处：《国际麻醉学与复苏杂志》2012年第3期207-211,共5页International Journal of Anesthesiology and Resuscitation

摘　　要：背景肝移植围手术期各类肺部并发症发生率高，发病机制复杂，严重影响患者的预后。目的分析肝移植围手术期肺部并发症的危险因素并提出具体防治措施以保护肺功能。内容介绍肝移植术后急性肺损伤（acute lung injury，ALI）的机理；患者术前病理生理因素、麻醉因素以及非特异性因素与肺部并发症的关系；围手术期肺功能保护的措施。趋向对相关机制和危险因素进行深入研究，并采取相应防治措施，有助于减少肝移植患者围手术期肺部并发症的发生。Background Perioperative pulmonary complications severely affects the prognosis of liver transplantation patients, because of its high incidence and complicated mechanism. Objective This article analyzed the risk factors of perioperative pulmonary complications in liver transplantation and introduced some preventive strategies to protect the pulmonary function. Content The mechanism of postoperative acute lung injury （ALI）, the relationships among preoperative pathophysiologic factors, anaesthesia factors, non-specific factors and pulmonary complications, as well as the perioperative pulmonary function protecting strategy were discussed. Trend Further research of mechanism and risk factor, combining with relevant strategies of prevention could reduce the incidence of pulmonary complications during the perioperative period of liver transplantation.

关 键 词：肝移植 围手术期 肺部并发症 

分 类 号：R657.3[医药卫生—外科学]