腹腔镜与中药结合治疗卵巢子宫内膜囊肿的临床研究  

Clinical Study on Endometrial Ovarian Cyst Treated by integrated Laparoscopy and Chinese Herbal Medicine

作　　者：吴育宁 华苓[1] 金延[1] 张晓辉[1] 石同淑[1] 付洁[1] 滕秀香[1] 

机构地区：[1]北京中医医院,北京100010

出　　处：《中国中西医结合杂志》2000年第3期183-186,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的：探索一种中西医结合治疗卵巢子宫内膜囊肿的新疗法。方法：１５２例卵巢子宫内膜囊肿患者随机采用腹腔镜与中药结合（中西医治疗组）、单纯中药（中药组）、单纯西药（西药组）三种不同方法治疗，观察其疗效及不良反应；并同时检测血清ＣＡ１２５、生殖内分泌激素及血浆前列腺素等。结果：中西医治疗组在囊肿体积缩小率、囊肿消失率、愈显率均优于单纯中药组及西药组（Ｐ＜ ０．０５， Ｐ＜ ０．０１）；妊娠率高于西药组（Ｐ＜Ｏ．０５）；无明显不良反应。中西医治疗组疗后血浆前列腺素明显下降（均Ｐ＜０．０１），血清孕酮上升（ Ｐ＜ ０．０５），ＣＡ１２５明显下降（ Ｐ ＜ ０．０１）。结论：腹腔镜与中药结合治疗卵巢子宫内膜囊肿是一种疗效较好、不良反应小、最大限度保留生育机能的新方法。To investigate a new method of integrated laparoscopy with Chinese herbal medicine (CHM) in treating endometrial ovarian cyst. Methods: One hundred and fifty-two patients with endometrial ovarian cyst were randomly treated with three therapies: Integrated laparoscopy with CHM (combination group), CHM (TCM group) and Danazol (WM group). To compare the clinical efficacy and side-effects of the three groups and to elucidate the therapeutic mechanism by detecting the serum CA125 reproductive endocrine hormone, plasma PGF1a. PGE2 etc. Results: The shrinking rate and disappearance rate of the cysts, and markedly effective rate of combination group were obviously higher than those of TCM group and WM group (P< 0. 05, P< 0.01). The pregnany rate of combination group was also higher than that of WM group (P< 0.5). Few sideeffects were the most prominent advantage for combination group and TCM group. After treatment, the plasma PGF1a. lowered remarkably, serum PO increased and CA125 reduced obviously (P< 0.01, P< 0.05). Conclusion: The integrated laparoscopy and CHM combination therapy is a new method in treating endometrial ovarian cyst with significant efficacy, minimal adverse effect and maximal preservation of reproductive function.

关 键 词：卵巢子宫内膜 囊肿 腹腔镜 中西医结合治疗 

分 类 号：R273[医药卫生—中西医结合]