桂林西瓜霜对宫颈糜烂组织细胞的影响研究  

Study on the effect of Guilin watermelon frost on cervical columnar ectopy tissue and cells

作　　者：董林红[1] 蒋秋燕[1] 宋金玲[2] 张琪[2] 李艳林[2] 莫海霞[2] 

机构地区：[1]广西中医学院第一附属医院,广西南宁530023 [2]广西中医学院

出　　处：《中国妇幼保健》2012年第7期1079-1081,共3页Maternal and Child Health Care of China

基　　金：2009年国家自然科学基金(30960482);2010年广西自然科学基金(2010GXNSFA013207)

摘　　要：目的:探讨桂林西瓜霜对宫颈糜烂组织细胞的影响。方法:将160例宫颈糜烂患者随机分为观察组和对照组,观察组用桂林西瓜霜喷敷宫颈糜烂面;对照组采用bFGF-胶原蛋白海绵外敷。光学显微镜下观察两组治疗前后的黏膜上皮细胞增生、炎细胞浸润、间质成纤维细胞增生情况。结果:观察组采用的桂林西瓜霜对鳞状上皮细胞增生、炎性细胞减少、肉芽组织及成纤维细胞形成、血管新生等有促进作用。经组织细胞病理形态学积分差比较,观察组对宫颈组织被覆上皮完好率高于对照组,经积分差u检验(P<0.05)差异有统计学意义;成纤维细胞增生积分差经u检验(P>0.05)差异无统计学意义。结论:桂林西瓜霜具有消炎抗菌、促进糜烂面愈合的作用。Objective： To explore the effect of Guilin watermelon frost on cervical columnar ectopy tissue and cells. Methods： One hundred and sixty patients with cervical columnar eetopy were randomly divided into observation group and control group ; the patients in observation group were treated with sprayed coating of Guilin watermelon frost on the erosion surface; while the patients in control group were treated with external application of bFGF - collagen sponge. The hyperplasia of mucosal epithelial ceils, inflammatory cell infiltration, and interstitial fibroblast proliferation in the two groups were observed under light microscope. Results： Guilin watermelon frost used in observation group had a promoting effect on hyperplasia of squamous epithelial cells, decrease of the inflammatory cells, formation of granulation tissue and fibroblast, and angiogenesis. The intact rate of covering epithelium of cervical tissue in observation group was significantly higher than that in control group （ P 〈 0. 05 ） . There was no significant difference in the integral difference of fibroblast proliferation between the two groups （ P 〉 0. 05 ） . Conclusion： Guilin watermelon frost has anti - inflammatory effect and anti - bacterial effect, which can promote the healing of the erosion surface.

关 键 词：桂林西瓜霜 宫颈糜烂 组织细胞 

分 类 号：R711.32[医药卫生—妇产科学]