正交试验法优选了哥王中西瑞香素的提取工艺  

Optimization of Extraction Technology for Daphnoretin from Wikstroemia indica by Orthogonal Test

作　　者：喻文进[1] 夏武云[1] 肖玥[1] 王定勇[1] 

机构地区：[1]广东药学院药科学院,广州510006

出　　处：《中国实验方剂学杂志》2012年第5期12-14,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广东省科技计划项目(2009B030801088)

摘　　要：目的:优选了哥王中西瑞香素的提取工艺。方法:采用单因素及正交试验,以西瑞香素含量为指标,考察超声功率、甲醇用量、提取时间、提取次数4个因素对提取工艺的影响,优选了哥王中西瑞香素的提取条件。结果:了哥王中西瑞香素的最佳提取工艺为16倍量甲醇超声提取2次,每次1.5 h,超声功率160 W。结论:提取工艺简单合理可行,可用于了哥王中西瑞香素的提取。Objective：To optimize optimum extraction process of daphnoretin from W.indica.Method：Orthogonal design test and single factor test was used to optimize extraction conditions of daphnoretin from W.indica with the content of daphnoretin as index,and investigated effect of ultrasonic power,amount of methanol,extraction time and extraction times on extraction technology.Result：Optimum extracting technology of daphnoretin from W.indica were： extracted 2 times with 16 times the amount of methanol for 1.5 h each time,ultrasonic power was 160 W.Conclusion：This optimized extraction technique was simple,reasonable and feasible,which could be used in extraction of daphnoretin from W.indica.

关 键 词：了哥王 西瑞香素 提取工艺 

分 类 号：R283.6[医药卫生—中药学]