保济丸粉辐照前后解热及止吐作用的研究  

Experimental Antipyretic and Antiemetic Effects of Baoji Wan Powder before and after Irradiation

作　　者：茹丽[1] 郭起岳[1] 许常辉[1] 

机构地区：[1]广州中医药大学科技产业园,广州510445

出　　处：《中国实验方剂学杂志》2012年第5期191-193,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:研究保济丸粉辐照前后的解热作用及止吐作用。方法:采用酵母菌复制大鼠发热模型,观察保济丸粉0.93,1.86,3.72 g.kg-1,ig 2次辐照前后的解热作用;采用硫酸铜复制家鸽呕吐模型,观察保济丸粉(0.93,1.86,3.72 g.kg-1,ig连续3 d)辐照前后的止吐作用。结果:保济丸粉辐照前后可显著降低酵母性发热大鼠的体温,与模型对照组比较,P<0.01,P<0.05;保济丸辐照前后均可显著减少硫酸铜致家鸽的呕吐次数,与模型对照组比较,P<0.05。结论:保济丸粉辐照前后具有解热及止吐作用,辐照前后的作用比较,差异无显著性。Objective：To study the experimental antipyretic and antiemetic effects of the powder of Baoji Wan before and after irradiation.Method：Rat fever model was established by yeast to observe the antipyretic effect of the powder of Baoji Wan before and after irradiation.Pigeon vomiting model was induced by using copper sulfate to investigate the antiemetic effect of the powder of Baoji Wan before and after irradiation.Result：The powder of Baoji Wan could significantly reduce the temperature of yeast-induced fever in rats before and after irradiation,compared with the control group（P0.01 and P0.05）.The powder of Baoji Wan could significantly reduce the number of copper sulfate-induced vomiting in pigeons,compared with the control group（P0.05）.Conclusion： The powder of Baoji Wan has antipyretic and antiemetic effects before and after irradiation.The effect＇s comparison for before and after irradiation,the difference was not significant.

关 键 词：保济丸 辐照 解热 止吐 

分 类 号：R285.5[医药卫生—中药学]