声触诊组织定量技术在甲状腺弥漫性病变诊断中的应用  

Application of Virtual Touch Tissue Quantification in Diagnosis of Diffuse Thyroid Disease

作　　者：胡智安[1] 韩鄂辉[1] 张频[1] 朱剑芳[2] 

机构地区：[1]黄石市中心医院超声科,湖北黄石435000 [2]南昌大学第一附属医院超声科,南昌330006

出　　处：《南昌大学学报（医学版）》2011年第12期47-49,53,F0003,共5页Journal of Nanchang University：Medical Sciences

摘　　要：目的探讨声触诊组织定量(virtual touch quantification,VTQ)技术对甲状腺弥漫性病变的诊断价值。方法应用VTQ技术对20例正常甲状腺者(正常对照组)和85例甲状腺弥漫性病变患者(病例组)进行检测,同时采用VTQ分析软件计算组织弹性顺应力的横向剪切波速度,分析甲状腺弥漫性病变的VTQ相关数据。结果正常对照组(正常甲状腺)横向剪切波速度值为(1.54±0.42)m.s-1,病例组中的单纯性甲状腺肿横向剪切波速度值为(1.83±0.31)m.s-1,甲状腺功能亢进横向剪切波速度值为(1.96±0.53)m.s-1,亚急性甲状腺炎横向剪切波速度值为(2.34±0.24)m.s-1,甲状腺功能减低横向剪切波速度值为(3.34±0.12)m.s-1,桥本甲状腺炎横向剪切波速度值为(3.83±0.37)m.s-1。病例组中的单纯性甲状腺肿、甲状腺功能亢进、亚急性甲状腺炎、甲状腺功能减低、桥本甲状腺炎横向剪切波速度值与正常对照组比较差异均有统计学意义(均P<0.05),单纯性甲状腺肿横向剪切波速度值与甲状腺功能亢进比较差异无统计学意义(P>0.05),甲状腺功能减低、亚急性甲状腺炎、桥本甲状腺炎横向剪切波速度值与单纯性甲状腺肿、甲状腺功能亢进比较差异均有统计学意义(均P<0.05),甲状腺功能减低、亚急性甲状腺炎横向剪切波速度值与桥本甲状腺炎比较差异均有统计学意义(P<0.01)。结论 VTQ技术在甲状腺弥漫性病变的诊断和鉴别诊断中具有较高的临床参考价值。Objective To explore the diagnostic value of virtual touch quantization（VTQ） in diffuse thyroid disease.Methods The VTQ technique was used in 85 patients with diffuse thyroid disease（case group） and 20 normal subjects（control group）.At the same time,transverse shear wave velocity was measured to calculate the elastic compliance using VTQ analysis software and the relevant data were analyzed for diffuse thyroid disease.Results Thetransverse shear wave velocity was（1.54±0.42）m·s-1,（1.83±0.31）m·s-1,（1.96±0.53）m·s-1,（2.34±0.24）m·s-1,（3.34±0.12） m·s-1 and（3.83±0.37）m·s-1in control,simple goiter,hyperthyroidism,subacute thyroiditis,hypothyroidism and Hashimoto＇s thyroiditis,respectively.Transverse shear wave velocity in control group was significantly greater than that in case group（all P0.05）,but there were no obvious differences between simple goiter and hyperthyroidism（P0.05）.Transverse shear wave velocities in subacute thyroiditis,hypothyroidism and Hashimoto＇s thyroiditis were significantly greater than those in simple goiter and hyperthyroidism（all P0.05）,and transverse shear wave velocities in hypothyroidism and subacute thyroiditis were obviously smaller than those in Hashimoto＇s thyroiditis（P0.01）.Conclusion The VTQ technology has high clinical reference value in the diagnosis and differential diagnosis of diffuse thyroid disease.

关 键 词：声触诊组织定量技术 弥漫性病变 甲状腺 超声检查 彩色 多普勒 

分 类 号：R445.1[医药卫生—影像医学与核医学]