潘托拉唑在胃溃疡中的临床应用价值  

The clinical application of pantoprazole in gastric ulcer

作　　者：刘恒新[1] 刘蕾[1] 

机构地区：[1]解放军第八十八医院消化科,山东泰安271000

出　　处：《中国当代医药》2011年第35期80-80,82,共2页China Modern Medicine

摘　　要：目的:探讨潘托拉唑在胃溃疡中的临床应用价值。方法:选择50例胃溃疡患者使用潘托拉唑联合阿莫西林和左氧氟沙星治疗,并与使用奥美拉唑联合阿莫西林和左氧氟沙星治疗的患者比较,治疗2、4周后比较两组患者临床症状消失率以及对幽门螺旋杆菌的根治作用,并统计治疗的不良反应。结果:两组治疗后2周临床症状消失率差异无统计学意义(P>0.05),治疗后4周观察组临床症状消失率明显大于对照组(P<0.05),观察组治疗后4周幽门螺杆菌根治明显高于对照组(P<0.05),两组患者不良反应发生率差异无统计学意义(P>0.05)。结论:对于单发胃溃疡患者使用潘托拉唑治疗,相对于奥美拉唑经济方便且有效率更高,是一种值得临床推广的方法。Objective： To investigate the clinical application of pantoprazole in gastric ulcer. Methods： 50 cases of gastric ulcer patients used amoxicillin and levofloxacin and then combined with pantoprazole and omeprazole, statistics the clinical symptoms and the rate of the cure for the role of helicobacter after 2 and 4 weeks pylori and statistical the adverse reac- tions. Results： The ratio had no significant difference between two groups with the clinical symptoms at the two weeks （P〉 0.05）, the clinical symptoms of treatment group was significantly greater than the control group at 4 weeks （P〈0.05）, pylorus group after treatment pylori cure was significantly higher than the control group at 4 weeks （P〈0.05）, the incidence of adverse reactions in both groups patients had no significant difference （P〉0.05）. Conclusion： For patients with single ulcer treatment pantoprazole compared to omoeprazole is more economical, convenient and efficient, it is an clinical efficacious methods.

关 键 词：潘托拉唑 胃溃疡 价值 临床应用 

分 类 号：R656.62[医药卫生—外科学]