骨骺干细胞研究现状  

Experimental Research of Osteoepiphysis Stem Cells

作　　者：赵友[1] 尹航[1] 王昌兴[1] 王哲[1] 

机构地区：[1]浙江中医药大学,浙江杭州310035

出　　处：《中华中医药学刊》2012年第2期346-348,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省教育厅资助项目(Y201016893)

摘　　要：骨骺干细胞又称前软骨细胞,存在于胚胎或新生动物四肢干骺端LaCroix环中的一种成体干细胞,其在体外有持续增值及定向分化的能力,是近年来研究发现的保持有干细胞特性的成体干细胞,它的分离和培养为未能找到理想种子来修复软骨缺损和退化所导致的临床一系列疾病的病人带来了希望。然而只分离出骨骺干细胞只是找到了种子来源,如何体外培养并调控骨骺干细胞使其保持生物学特性成为近年来实验研究的热点。Precartilagious stem cells, known as stem cells, presenting in embryonic or newborn animals limbs LaC- mix ring is adult stem cells. It has the ability to persistly proliterate and make directed differentiation of value - added in vitro. Researchers have found that stem cells maintain characteristics of adult stem cells in recent years, whose isolation and culture bring hope to patients who have diseases caused by cartilage defects and degradation. Doctors have not found the perfect seeds for the patients. Although epiphysis stem cells isolated from the seed source is found, how to control the epiphysis in vitro and to keep biological characteristics of stem cells is a popular experimental study in recent!years.

关 键 词：骨骺干细胞 成纤维细胞生长因子-3 中医药 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]