妊娠期高血压疾病患者动脉硬化指数水平变化  

Changes of arteriosclerosis index level in women with pregnancy induced hypertension

作　　者：周丽琴[1] 

机构地区：[1]苏州市相城人民医院,江苏苏州215000

出　　处：《医药论坛杂志》2011年第24期74-75,共2页Journal of Medical Forum

摘　　要：目的检测妊娠期高血压患者及子痫前期(包括轻度和重度)患者血清中胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)水平,运用公式动脉硬化指数[AI=(TC-HDL-C)/HDL-C]以探讨妊娠期高血压疾病发病中动脉硬化指数水平变化。方法应用酶法及间接沉淀法检测50例妊娠期高血压患者(妊高组)、30例子痫前期患者及50例正常妊娠妇女(对照组)血清中胆固醇(TC)及高密度脂蛋白胆固醇(HDL-C)水平。结果妊高组血清中动脉硬化指数水平高于对照组,子痫前期组血清中动脉硬化指数水平明显高于妊高组及对照组,且有显著性差异(P<0.05)。结论动脉硬化指数水平与妊娠高血压疾病密切相关,且与疾病的严重程度呈正比。Objective To examine serum total cholesterol（TC）and high density lipoprotein cholesterol（HDL-C） level in woman with Pregnancy induced hypertension（PIH）,arteriosclerosis index（AI）=（TC-HDL-C）/HDL-C,and elucidate the effect of it on the development of the disease.Methods Serum total cholesterol（TC）and high density lipoprotein cholesterol（HDL-C） level were measured in 50 normal pregnant women（control group）,50 pregnant women with gestational hypertension（GH group）and 30 pregnant woman with Pre-Eclampsia（Pre-Eclampsia group）.The Pre-Eclampsia group was further divided into the following subgroup： mild,and severe Pre-Eclampsia group.We used indirect-precipitation and enzymic method to measure serum total cholesterol（TC）and high density lipoprotein cholesterol（HDL-C） level.Results The AI levels were found significant higher in gestational Hypertension group than that in control group,The AI levels were higher in all Pre-Eclampsia subgroups than that in control,and higher than gestational Hypertension group,Result is statistically significant（P0.05）.Conclusions This study has demonstrated that AI levels are elevated in pregnant woman with PIH and associated with severity of the disease.

关 键 词：妊娠期高血压疾病 动脉硬化 子痫前期 

分 类 号：R714.246[医药卫生—妇产科学]