普米克令舒与氨溴索雾化吸入治疗慢性阻塞性肺疾病效果观察  

Effect observation of Pulmicort combined with inhalation of ambroxol treatment of chronic obstructive pulmonary disease

作　　者：王里松[1] 

机构地区：[1]亳州市人民医院呼吸内科,安徽亳州236800

出　　处：《医药论坛杂志》2011年第24期108-109,111,共3页Journal of Medical Forum

摘　　要：目的研究普米克令舒与氨溴索氧气驱动气雾吸入治疗慢性阻塞性肺疾病(C0PD)的临床疗效。方法将90例COPD患者按入院先后顺序分为治疗组与对照组,每组45例。在常规使用敏感抗生素、解痉平喘、化痰治疗基础上,治疗组用氨溴索30mg加生理盐水10ml雾化吸入,对照组采用传统糜蛋白酶4000U加生理盐水10ml加庆大霉素8万U加地塞米松5mg进行雾化吸入。比较两组患者雾化吸入后祛痰效果、肺功能变化及患者的住院天数。结果治疗后气短、呼吸困难症状的改善治疗组超过对照组,两组有显著性差异(P<0.05);肺功能方面治疗组治疗前后差异有显著性(P<0.01);治疗组住院天数(11.57±2.14)d少于对照组住院天数(15.37±2.46)d,两组比较差异有统计学意义(P<0.01)。结论普米克令舒联合氨溴索氧气驱动气雾吸入治疗COPD,促进排痰、祛痰,畅通呼吸道,改善肺功能,缩短住院天数,是一种安全、有效的方法。Objective To study the clinical efficacy of Pulmicort and ambroxol oxygen-driven aerosol in treatment of chronic obstructive pulmonary disease（C0PD）.Methods Totally 90 COPD patients according to admission order is divided into treatment group and control group each 45 cases.Sensitive to the routine use of antibiotics,antispasmodic asthma,phlegm treatment based on the treatment group with saline 10ml ambroxol 30mg inhalation in the control group using traditional chymotrypsin 4000U saline 10ml gentamicin 80000 U to plug betamethasone 5mg for inhalation.Two groups were compared after inhalation expectorant effects,lung function changes and the patient＇s hospital stay.Results After treatment,shortness of breath,dyspnea improvement in the treatment group were beffer than those the control group,significant difference between the two groups（P0.05）;Lung function before and after treatment was significant difference（P0.01）;Inpatient treatment group number of days（11.57±2.14） than the control group the number of hospital days（15.37±2.46）,the difference was statistically significant（P0.01）.Conclusions Pulmicort joint ambroxol oxygen-driven aerosol inhalation COPD,can promote expectoration,phlegm,respiratory flow,improve lung function and shorten hospital stay,is a safe and effective method.

关 键 词：氨溴索 普米克令舒 气雾吸入 慢性阻塞性肺疾病 

分 类 号：R563[医药卫生—呼吸系统]