益气破血行气通络中药对乙型肝炎代偿期肝硬化患者的治疗作用  

Effects of Qi-invigorating and blood-breaking medicine on hepatic fibrosis in patients with compensated cirrhosis of chronic hepatitis B

作　　者：王仲霞[1] 王立福[1] 王葽[1] 杨慧银[1] 周双男[1] 白云峰[1] 朱云[1] 侯宝国 李永纲[1] 

机构地区：[1]解放军第302医院中西医结合肝病1科,北京100039 [2]河北省唐山市玉田县医院

出　　处：《中西医结合肝病杂志》2012年第1期5-7,共3页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

基　　金：国家科技重大专项<中医药防治病毒性肝炎的行气通络临床科研基地建设>资助(No.2009ZX10005-017)

摘　　要：目的:探讨益气破血行气通络中药治疗乙型肝炎代偿期肝硬化患者,对其肝纤维化程度的影响。方法:60例乙型肝炎代偿期肝硬化患者随机分为治疗组(中药+恩替卡韦)和对照组(恩替卡韦),临床观察24周,以无创肝纤维化Fibroscan的肝脏硬度值及肝纤维化4项指标评价疗效。结果:治疗组患者24周后肝脏硬度值及肝纤维化4项指标下降均明显高于对照组,P<0.05。结论:益气破血行气通络中药治疗乙型肝炎代偿期肝硬化疗效显著。Objective：To discuss the effects of traditional Chinese medicine,which was based on the Qi-invigorating and blood-breaking theory,on hepatic fibrosis in patients with compensated cirrhosis of chronic hepatitis B.Methods：Sixty patients were randomly divided into 2 groups,the TCM group and the control group.After 24 weeks treatment,efficacies were evaluated by fibroscan and 4 indexes of hepatic fibrosis.Results：Stiffness of fibroscan and hepatic fibrosis indexes were better in the TCM group than in the control group,P0.05.Conclusion：Qi-invigorating and blood-breaking medicine can effectively decrease the indexes of hepatic fibrosis and stiffness of fibroscan in patients with compensated cirrhosis of chronic hepatitis B..

关 键 词：肝炎乙型 慢性 代偿期肝硬化 纤维化 中药 破血理论 瞬时肝脏弹性扫描 

分 类 号：R259[医药卫生—中西医结合]