毛细管准直微束过程模拟与微束品质分析  

Collimation process simulation and beam quality analysis of capillary-based microbeam

作　　者：柳岸[1,2] 李嘉庆[1,2] 王旭飞[1,2] 张杰雄[1,2] 王建中[1,2] 张伟[1,2] 张斌[1,2] 邵春林[3] 施立群[1,2] 

机构地区：[1]复旦大学核科学与技术系,现代物理研究所,上海200433 [2]复旦大学离子束应用物理教育部重点实验室,上海200433 [3]复旦大学放射医学研究所,上海200032

出　　处：《强激光与粒子束》2012年第1期202-206,共5页High Power Laser and Particle Beams

基　　金：国家自然科学基金青年科学基金项目(11005019);上海市重点学科建设项目(B107)

摘　　要：利用GEANT4程序对复旦大学单粒子微束的毛细管准直过程进行了蒙特卡罗模拟。计算结果表明:当前采用的1μm孔径、1 mm长度的毛细玻璃管准直器能够引出峰值能量2.2 MeV、能量分辨130 keV、束径2.4μm的质子微束,可达到装置对微束能量与束径分辨的设计指标,从理论上明确了毛细管准直微束引出的可行性。针对影响入射目标细胞微束品质的主要因素,分析了微束品质与准直系统和入射束流各状态参数的依赖关系,为毛细管准直微束的引出与优化提供了必要的理论依据。A GEANT4 based Monte-Carlo simulation on collimation processes of single-particle microbeam at Fudan University by capillary collimator was performed with regard to the incident beam parameters, including the divergent angle of incident beam, the incident beam energy, the misalignment angle of beam collimation and the length of collimator. As a result, a proton beam with 2.2 MeV peak energy and 130 keV FWHM which was 2.4 μm in radius, was acquired by the collimator which was 1 gm in diameter, and 1 mm in length, meeting the requirements of design. The simulation shows the possibility of acquiring mi- crobeams in micron scale, and reveals the relationship of system design parameters and incident beam parameters with capillary- based microbeam, which determines the quality of mierobeam and as it irradiates the cells.

关 键 词：单粒子微束 毛细管准直器 微束品质 细胞照射 

分 类 号：TL99[核科学技术—核技术及应用] O57[理学—粒子物理与原子核物理]