Rh(D)阴性献血者不规则抗体检测的结果分析  

Analysis the result of irregular antibody test in Rh(D) negative donors

作　　者：李健[1] 周英[1] 吕文彬[1] 陈雪[1] 迭敏[1] 龚希 

机构地区：[1]成都市血液中心,四川成都610041 [2]成都市郫县疾病预防控制中心,四川成都611730

出　　处：《四川医学》2012年第2期341-343,共3页Sichuan Medical Journal

摘　　要：目的分析Rh(D)阴性献血者不规则抗体检测的结果,探讨在献血者血液Rh(D)阴性确认试验时,进行不规则抗体检测的必要性。方法用间接抗人球蛋白法进行Rh(D)阴性确认试验及抗体筛选试验、抗体鉴定试验,盐水法进行Rh表现型的检测。结果 1205份Rh(D)阴性献血员标本中,抗体筛选试验阳性的标本有20份,经过抗体鉴定,其中抗-D 10份,抗-M 6份,非特异性抗体2份,抗-Lea1份,冷自身抗体1份。结论 Rh(D)阴性献血者抗体筛选阳性率高达1.66%,较以往报道的正常人群抗体筛选阳性率高。在临床供血上,其高检出率对临床用血安全有较为重要的意义,对Rh(D)阴性献血者更应该进行不规则抗体检测。Objective To analyze the result of irregular antibody test in Rh（D） negatie donors,discuss in the necessity of irregular antibody test in Rh（D） negative confirmation experiment among the blood testing with Rh（D） negative donors.Methods Rh（D） negative confirmation experiment antibody screening and antibody Identification test using indirect antiglobulin test（IAT）,The Rh phenotype were determined by saline method.Results among 1205 samples of Rh（D） negative donors,20 samples antibody screening test is positive.And after antibody Identification test,Among them 10 samples were anti-D,6 samples were anti-M,2 samples were Nonspecific antibody,1 sample was anti-Lea,1 sample was cold antibody.Conclusion The positive rate of Antibody screening in Rh（D） negative donors is 1.66%.it is greater than Previous reports of the normal population positive antibody screening.the higher positive rate of Antibody screening has Important clinical significance in blood supply.therefore Rh（D） negative donors more should do irregular antibody test.

关 键 词：RH(D)阴性 献血者 抗体筛查 抗体鉴定 

分 类 号：R446.6[医药卫生—诊断学]