胸椎旁注射治疗带状疱疹后神经痛  

Clinical efficacy of thoracic paravertebral injection in post-herpetic neuralgia cases

作　　者：施小妹[1] 宋涛[1] 王秋石[1] 崔文瑶[1] 奚奇[1] 吴兆奇[1] 

机构地区：[1]中国医科大学附属第一医院麻醉科,沈阳110001

出　　处：《实用药物与临床》2012年第2期70-72,共3页Practical Pharmacy and Clinical Remedies

基　　金：辽宁省博士启动基金资助项目(20071045);教育部留学回国人员科研启动基金资助项目(教外司留[2009]8号)

摘　　要：目的研究胸椎旁注射治疗胸背部带状疱疹后神经痛的疗效。方法胸背部带状疱疹后神经痛患者30例,给予胸椎旁注射,药物:神经妥乐平、得宝松、利多卡因、罗哌卡因。每周1次,共4周。记录治疗前后的VAS值,匹兹堡睡眠质量指数PSQI,是否存在痛觉超敏以及治疗过程中的不良反应。结果与治疗前比较,VAS值和PSQI均显著降低(P<0.01);VAS值:前3次注射每次均较上一次显著降低,但第4次与第3次比较,差异无统计学意义;痛觉超敏缓解率为78.26%;胸椎旁注射治疗中和治疗后未出现明显不良反应。结论胸椎旁注射治疗带状疱疹后神经痛疗效确切,安全可行。但3次以上的治疗则无必要。Objective To analyze the effects of thoracic paravertebral injection on post-herpetic neuralgia patients.Methods 30 patients underwent post-herpetic neuralgia received thoracic paravertebral injection with neurotropin,diprospan,lidocaine and ropivacaine weekly for 4 weeks.The pain intensity,sleep quality,symptom of allodynia and side effects during the therapy were observed.The intensity of pain was assessed by Visual analogue scale（VAS）,and the quality of sleep was measured by Pittsburge sleep quality index（PSQI）.Results The VAS and PSQI decreased definitely（P0.01）,each injection showed definite reduction on VAS compared with the last one except the fourth injection,and the symptom of allodynia was mostly cured（78.26%）.No obvious side effect was found.Conclusion Thoracic paravertebral injection is effective and safe for post-herpetic neuralgia patients and injection for more than three times is unnecessary.

关 键 词：带状疱疹后神经痛 胸椎旁注射 神经源性炎症 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]