联会复合体的组成、功能及遗传控制  

Organization,function and genetic controlling of synaptonemal complex

作　　者：谢文军[1] 史典义[1] 蔡泽熙[1] 陈晓阳[2] 金危危 

机构地区：[1]中国农业大学国家玉米改良中心,农业部作物遗传改良基因组研究重点实验室,北京100193 [2]湖南农业大学农学院,长沙410128

出　　处：《遗传》2012年第2期167-176,共10页Hereditas（Beijing)

基　　金：国家重点基础研究发展规划项目(“973计划”)(编号:2011CB944600)资助

摘　　要：在多数有性生殖生物中,减数分裂第一次分裂前期同源染色体间会形成一种复杂的超级蛋白结构——联会复合体(Synaptonemal complex,SC)。该结构与同源染色体间的配对、联会、交换、分离等过程密切相关。若其出现异常,将可导致性母细胞大量凋亡,宏观上即表现为生物个体不育。近年来,该结构已成为减数分裂研究领域的一个热点,但其控制机理至今所知还十分有限。文章对联会复合体的组成、功能及其遗传控制等情况进行概述,并对其未来的研究进行探讨和展望。The synaptonemal complex(SC) is a super protein lattice that connects paired homologous chromosomes in most meiotic systems.This special organization is related to the meiosis processes such as homologous chromosomes pair-ing,synapsis,recombination,segregation,etc.Flaws of it would lead the meiocytes to apoptosis,which contributes to steril-ity.In recent years,the study of this complex has been a hotspot in meiosis research,but little was known about its exact mechanism.This review summarized the organization,function,and genetics of this complex with recent advances.Pros-pects of its further study were also briefly discussed.

关 键 词：联会复合体 同源匹配 配对 重组 减数分裂 不育 

分 类 号：Q343[生物学—遗传学]