移植胚胎选择的量化指标  

Quantitative Clinical Standard of Embryo Selection

作　　者：张宁锋[1] 陈静华[1] 王文军[1] 李瑞岐[1] 欧阳能勇[1] 马芸[1] 麦美琪[1] 

机构地区：[1]中山大学孙逸仙纪念医院生殖医学中心,广州广东510120

出　　处：《中山大学学报（医学科学版）》2012年第1期131-135,共5页Journal of Sun Yat-Sen University:Medical Sciences

摘　　要：【目的】探讨胚胎累计评分(ECS)预测胚胎发育潜能及胚胎种植率(IR)和临床妊娠率(PR)的价值。【方法】782个IVF周期及223个ICSI周期分别计算ESC,并依据ESC及种植率和妊娠率做频数表,并分别分为妊娠与非妊娠组进行比较ESC。【结果】IVF周期在ESC大于18且不大于32时和ICSI周期在ESC大于22且不大于32时可以达到50%以上妊娠率,此范围外ESC均致使妊娠率降低;IVF周期在ESC大于28且不大于32时和ICSI周期在ESC大于26且不大于32时可以达到35%以上种植率,此范围外ESC均致使种植率降低;两种周期妊娠组ESC均高于未妊娠组(P<0.01)。【结论】ESC可以预测胚胎移植后的临床妊娠率,并为临床移植胚胎挑选提供量化标准。[Objective] To investigate the predict value of the developmental potential of embryos and embryo implantation rate （IR） and clinical pregnancy rate （PR） with cumulative embryo score （embryo cumulative score, ECS）. [Methods] ESC of 782 IVF cycles and 223 ICSI cycles were calculated, And frequency tables based on ESC and IR and PR were done, then ESCs were compared between pregnant and non-pregnant group. [Results] The PR was more than 50% when ESC was bigger than 18 and not bigger than 32 in IVF cycles and ESC was bigger than 22 and not bigger than 32 in ICSI cycles, ESC out of these scope causes decreasing of PR. The IR was more than 35% when ESC was bigger than 28 and not bigger than 32 in IVF cycles and ESC was bigger than 26 and not bigger than 32 in ICSI cycles, ESC out of these scope causes decreasing of IR. Two periods of projects showed that ESC of pregnancy group were higher than non-pregnant group （P 〈 0.01 ）. [Conclusion] ESC can predict the clinical pregnancy rate after embryo transfer, and provide a quantitative clinical standard for embryo selection.

关 键 词：体外受精-胚胎移植 胚胎评分 妊娠率 

分 类 号：R321-33[医药卫生—人体解剖和组织胚胎学]