鸡眼草3种不同溶剂提取物对ABTS自由基和羟自由基清除活性的研究  

Scavenging Activity of Different Extracts of Kummerowia striata on ABTS Radical and Hydroxyl Radical

作　　者：李培源[1] 霍丽妮[1] 苏炜[2] 邓超澄[1] 滕明敏[1] 卢澄生[1] 

机构地区：[1]广西中医学院药学院,南宁530001 [2]广西师范学院化学与生命科学学院,南宁530001

出　　处：《中国药房》2012年第11期964-966,共3页China Pharmacy

基　　金：教育部科学技术研究重点项目(210168)

摘　　要：目的:研究鸡眼草3种不同溶剂提取物对ABTS自由基(ABTS·+)和羟自由基(·OH)的清除活性。方法:用冷浸法得到鸡眼草乙醇、丙酮和乙酸乙酯提取物,以UV法测定3种提取物的总黄酮含量,并测定3种提取物对ABTS·+和·OH的清除活性。结果:鸡眼草丙酮提取物的总黄酮含量最高(131.41mg·g-1),对自由基的清除效果也最好,其对ABTS·+和·OH的清除率最高可达到88.79%和95.81%。结论:鸡眼草乙醇、丙酮和乙酸乙酯提取物都具有较强的自由基清除能力,有作为天然抗氧化剂开发利用的潜力。OBJECTIVE： To study the scavenging activity of 3 extracts of Kummerowia striata on ABTS and hydroxyl free radical. METHODS： The ethanol, acetone and ethyl acetate extracts were obtained by cold-extraction, then the total flavonoid content was determined by UV method and their scavenging activities on ABTS and hydroxyl radical were studied. RESULTS： The content of total flavonoid in acetone extract was the highest （131.41 mg.g^-1）, and it also exhibited the most remarkable scavenging activity on the above two free radicals, with the highest scavenging capacity of 88.79% and 95.81%, respectively. CONCLUSION： All the three extracts of K. striata have prominent antiradical activity, which possessed the potential to be natural antioxidants.

关 键 词：鸡眼草 提取物 自由基清除活性 

分 类 号：R285[医药卫生—中药学] R97[医药卫生—中医学]