创制杀菌剂烯肟菌酯异构体的鉴定及杀菌活性  

Identification of the Isomers of a Novel Fungicide Enestroburin and their Fungicidal Activities

作　　者：孙克[1] 吕良忠[1] 司乃国[1] 吴鸿飞[1] 李志念[1] 王凤宇[1] 曹巍[1] 

机构地区：[1]沈阳化工研究院有限公司新农药创制与开发国家重点实验室,沈阳110021

出　　处：《农药》2012年第3期168-171,共4页Agrochemicals

基　　金：国家重点基础研究发展计划(973计划)项目(2010CB735601);(2012CB724501);国家"十二.五"科技支撑计划项目(2011BAE06B00)

摘　　要：[目的]对烯肟菌酯异构体进行分离以及4个异构体的杀菌活性进行研究。[方法]柱层析法分离异构体,质谱和核磁进行结构鉴定。[结果]确定了烯肟菌酯4个异构体的空间构型,对黄瓜霜霉病、小麦白粉病的杀菌活性进行测定。[结论]烯肟菌酯的(E,E)和(E,Z)构型的2个异构体表现出很好的杀菌活性。[Aims] Four isomers of a novel fungicide enestroburin were separated and their fungicidal activities were studied.[Methods] The isomers were separated by column chromatography and the structures were confirmed by MS and 1H NMR spectroscopy.[Results] The stereo configurations of the isomers were confirmed and the isomers were tested against cucumber downy mildew and wheat powdery mildew respectively.[Conclusions] The bioactivity results showed that the（E,E）and（E,Z） isomers exhibit good antifungal activity.

关 键 词：烯肟菌酯 异构体 杀菌活性 

分 类 号：TQ455[化学工程—农药化工]