水中尸体软组织生物力学性状时序性变化用于死亡时间推断  

Changes of Biomechanical Properties of Soft Tissues in Underwater Corpse for Postmortem Interval Estimation

作　　者：唐谷[1] 周晖[2] 汪家文[1,3] 钱红[1] 赖跃[2] 于晓军[1] 

机构地区：[1]汕头大学医学院法医教研室,广东汕头515041 [2]深圳市公安局刑事科学技术研究所,广东深圳518040 [3]佛山大学医学院病理教研室,广东佛山528000

出　　处：《法医学杂志》2012年第1期6-11,共6页Journal of Forensic Medicine

基　　金：国家自然科学基金资助项目(30772458;81072508)

摘　　要：目的探讨水中浸泡尸体软组织生物力学性状的时序性变化规律及其用于PMI推断的价值。方法SD大鼠颈椎脱臼处死后恒温下置于自来水中浸泡,按死后0、6、12、18、24、30、36、42、48、60、72、96、120、144、168、192 h时间点分组,分别取血管壁、皮肤、肌肉、小肠和结肠组织,应用万能材料试验机检测各组织的极限载荷、应变、最大应力等生物力学参数。结果除血管壁外,皮肤、肌肉、小肠和结肠等软组织的生物力学性状均随死亡时间呈逐渐下降时序性变化,存在各自不同的与PMI明显线性关系的"窗口期"。结论水中尸体软组织的生物力学性状的时序性变化与PMI之间存在一定规律性相关,可作为推断PMI的一种简便和量化的新技术手段。尸体周围散热介质的比热容可能是影响尸温、组织自溶腐败及其生物力学性状的物理学因素之一。Objective To explore the postmortem changes of biomechanical properties of underwater corpses and value for estimating postmortem interval.Methods SD rats were sacrificed by cervical vertebra dislocation and stored in the water at constant temperature.The vessel wall,skin,muscle,small intestine and colon were sampled at different postmortem time points（0 h,6 h,12 h,18 h,24 h,30 h,36 h,42 h,48 h,60 h,72 h,96 h,120 h,144 h,168 h,192 h）.The biomechanics properties of different soft tissues including ultimate load,strain,maximum stress were measured by electronic universal material testing machine.Results Except for the vessel wall,the biomechanics properties of skin,muscle,small intestine and colon showed linear decrease gradually after death.Each tissue displayed its obvious ＂window period＂ for PMI estimation.Conclusion The time-sequential changes of biomechanical property parameters of soft tissue in underwater corpses are significantly correlated with PMI and it could be a simple and quantitive new technology for estimating PMI.The specific heat capacity of the heat-eliminating medium around the corpses probably is one of the physical factors to influence algor mortis,autolysis,putrefaction and biomechanics properties.

关 键 词：法医病理学 生物力学 死亡时间 软组织 大鼠 

分 类 号：DF795.1[医药卫生—法医学]