头低位-30°卧床肺循环血液动力学的改变  

Hemodynamic Changes of Pulmonary Circulation During HDT-30°.

作　　者：仲崇发[1] 鲁力立[1] 杨静生[1] 赵国璇[1] 

机构地区：[1]航天医学工程研究所,北京100094

出　　处：《航天医学与医学工程》2000年第1期38-41,共4页Space Medicine & Medical Engineering

摘　　要：目的观察模拟失重条件下心肺循环变化的特点。方法采用超声多谱勒技术对１２ 名健康男性青年，在头低位－ ３０°４５ ｍｉｎ 时，测量了心功能的变化。结果 实验中右心室射血时间显著增加（ Ｐ＜ ０ ．０５） ，肺动脉最大血流速度显著下降（ Ｐ＜ ０ ．０５） ，肺动脉血流加速时间延长，右心室心输出量在１０ ｍｉｎ 、３０ ｍｉｎ 显著下降（ Ｐ＜ ０ ．０５） ，心率、右心室心搏量、肺动脉平均血流速度、肺动脉血流加速度均有下降的趋势，但不具有显著性。左心室输出量、左心室心搏量及血压的变化趋势与国内外报道的相似。结论从右心功能的各个参数的变化，提示在头低位的实验过程中肺循环阻力增高，阻力的增加是肺动脉压增高的直接原因。Objective To study the hemodynamic changes of pulmonary circulation during simulated weightlessness. Method 12 subjects were studied using echocardiography and electrocardiography during head down tilt(HDT) of -30° lasting for 45 min. Result Right ventricular ejection time increased significantly (P<0.05); peak velocity of pulmonary arterial blood flow decreased significantly (P<0.05); acceleration time of pulmonary arterial blood flow did not change significantly; significant decrease of right ventricular output occurred at the 10th minute and the 30th minute(P<0.05); pre ejection period significantly decreased at the 30th minute and recovery. Heart rate, mean velocity of pulmonary arterial blood flow,and acceleration of pulmonary arterial blood flow did not change significantly; left ventricular cardiac output, stroke volume and blood pressure remained constant throughout the experiment. Conclusion Changes of the parameters of pulmonary circulation suggested that pulmonary resistance increased, and the increase of pulmonary resistance maybe be the direct cause of the increase of pulmonary arterial pressure.

关 键 词：失重模拟 肺循环 血液动力学 头倒位倾斜 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]