老年高血压患者脉压与微量白蛋白尿的关系  

Relationship between pulse pressure and urine microalbuminuria in the elderly with essential hypertension

作　　者：朱长琪[1] 杨静[1] 

机构地区：[1]安徽合肥市第一人民医院急诊内科,230061

出　　处：《中国临床保健杂志》2012年第1期32-33,共2页Chinese Journal of Clinical Healthcare

摘　　要：目的研究老年高血压患者脉压与微量白蛋白尿之间的关系。方法将131例老年原发性高血压患者根据脉压水平分为4组(<50 mm Hg,50～59 mm Hg,60～69 mm Hg,>70 mm Hg),所有患者入选时血尿素氮、肌酐和24 h尿蛋白总量均在正常范围内。取晨尿用免疫散射法测定尿白蛋白含量,计算尿白蛋白排泄率(UAER)。结果 25例脉压<50 mm Hg者,UAER为(3.5±1.2)μg/min;31例脉压50～60 mm Hg者,UAER为(9.3±7.2)μg/min;23例脉压60～70 mm Hg者,UAER为(29.6±32.1)μg/min;52例脉压70 mm Hg以上者,UAER为(51.7±31.8)μg/min。随着脉压的增高,老年高血压患者的UAER也随之增高。结论脉压可作为老年高血压患者肾损害的高危预测指标之一。Objective To study the relationship between pulse pressure and urine microalbuminuria in aged patients with hypertension.Methods 131 elderly hypertesion patients with normal serum urea nitrogen（Bun）,creatinine（Cr）and 24h urine protein were divided into four groups by the level of pulse pressure（PP）（50 mmHg,50-59 mmHg,60-69 mmHg,70 mmHg）.Urine albumin were determined by immunonephelometric methud.Results Among the four groups,the levels of UAER increased gradually with the PP levels（P0.01）.Conclusion PP is one of the high risk factors of renal damage in patients with hypertension.

关 键 词：高血压 白蛋白尿 血压 危险因素 老年人 

分 类 号：R544.1[医药卫生—心血管疾病]