克山病病区粮多不饱和脂肪酸和硒水平  

Levels of polyunsaturated fatty acids and selenium in cereals from Keshan disease endemic areas

作　　者：姜熙罗[1] 安汝国[1] 刘景英[1] 金贞燕[1] 梁歧[2] 金卫东[2] 卢亦军[2] 

机构地区：[1]白求恩医科大学地方病研究所 [2]吉林省农业科学院大豆研究所

出　　处：《中国地方病学杂志》1990年第5期285-287,共3页Chinese Jouranl of Endemiology

摘　　要：克山病病区小麦亚油酸和亚麻酸含量分别为13.1±1.4g/kg 和1.05±0.13g/kg,非病区分别为10.3±2.2g/kg 和 0.71±0.19g/kg,病区明显高于非病区;病区玉米亚油酸和亚麻酸含量分别为28.1±0.22g/kg 和0.68±0.03g/kg,非病区分别为23.3±2.0g/kg 和0.57±0.07g/kg,亦病区明显高于非病区。病区小麦和玉米硒含量明显低于非病区。多不饱和脂肪酸与硒含量之间呈负相关,且均具有统计学意义。文中讨论了多不饱和脂肪酸负荷在克山病发病学中可能具有的意义。Contents of polyunsatueated fatty acids(PUFA)and selenium in wheat andmaize from Keshan disease endemic areas and nonendemic areas were determined.Linoleic and linolenic acid contents in wheat feom Keshan disease endemicareas were 27% and 49% higher than nonendemic areas respectively。Linoleic andlinolenic acid contents in maize from endemic areas were 20% and 18% higherthan nonendemic areas respectively.Selenium contents in both wheat and maizeform endemic areas were markedly lower than those from nonendemic areas.Th-ere were negative correlation between the contents of PUFA and selenium incereals.In addition to the selenium deficiency,it is inferred that PUFA overload andVE relative deficiency might also play an important role in the occurrence ofKeshan disease.

关 键 词：脂肪酸 PUFA 硒 克山病 

分 类 号：R542.302[医药卫生—心血管疾病]