基于对80例慢性肾脏病患者炎症干预的研究探讨药浴疗法“洁净府”机制  

Discussion on the mechanism of medicated bath ‘clear kideny' by interfering the nephritis of 80 CKD patients

作　　者：马俊杰[1] 周春祥[1] 

机构地区：[1]南京中医药大学,南京210046

出　　处：《中华中医药杂志》2012年第3期591-593,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金："十一五"国家科技支撑计划(No.2008BAI53B068)~~

摘　　要：目的:观察药浴疗法对慢性肾脏病的疗效及对免疫性炎症的作用,在此基础上探讨中医"洁净府"的机制。方法:80例慢性肾脏病患者随机分为2组,药浴组40例在现代医学一体化治疗的基础上配合药浴治疗,对照组为40例单纯一体化治疗,30d为1个疗程,在治疗前后分别测定血肌酐(Scr)、血清C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-αTNF-α)、血管紧张素Ⅱ(AngⅡ)及D-二聚体(D-dimer)。结果:药浴组治疗后患者的Scr、hs-CRP、IL-6、TNF-α、AngⅡ、D-dimer水平与本组治疗前及对照组治疗后比较差异有统计学意义(P<0.05)。结论:药浴对慢性肾脏病免疫性炎症有调节作用,此为其"洁净府"的机制之一。Objective： Discuss the mechanism of Medicated bath’clear kideny’by interfering the nephritis of 80 CKD patients.Methods： set the inclusion criteria and divided 80 CKD patients with chronic kidney into the medicated bath group（40 cases） and control group（40 cases）.To determinate serum creatinine,hs-CRP,IL-6,TNF-α,Ang Ⅱ and D-dimer before and after 30 day’s treatment.The data were analyzed on by statistical.Results： Serum creatinine,hs-CRP,IL-6,TNF-α,Ang Ⅱ,D-dimer were statistically significant differences between the medicated bath group and control group before and after treatment.Conclusion： Medicated bath have effect on the nephritis,that is one of the mechanism of Medicated bath’clear kideny’.

关 键 词：药浴 洁净府 慢性肾脏病 炎症 

分 类 号：R692[医药卫生—泌尿科学]