狗皮膏皮肤用药安全性实验研究  

Experimental Study on the Safety of Gou-pi Plaster

作　　者：曾勇[1] 赵贵琴[1] 陈怀斌 李帆帆[1] 孟宪丽[1] 

机构地区：[1]成都中医药大学中药材标准化教育部重点实验室,中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川成都610075 [2]四川省天全县中医医院,625500

出　　处：《时珍国医国药》2012年第2期375-376,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家“十一五”科技支撑计划(No.2008BAI53B082)

摘　　要：目的探讨狗皮膏皮肤用药安全性研究。方法对家兔进行皮肤急性毒性实验、皮肤刺激性实验,对豚鼠进行皮肤过敏实验。结果狗皮膏对家兔皮肤未引起急性毒性反应和刺激性反应,对豚鼠无致敏作用。结论狗皮膏是一种安全性较好的外用药。Objective To discuss the safety of Gou - pi plaster on skin treatment. Methods The skin acute toxicity experiment and skin irritating quality experiment were carried on the rabbits;the skin sensibility experiment was carried on the guinea pigs. Results Gou -pi piaster did not cause acute toxic reaction and excitant reaction on rabbit skin, and had no sensitization effect on guinea pigs. Conclusion Gou - pi plaster has food security for external use.

关 键 词：狗皮膏 皮肤急性毒性 皮肤刺激性 皮肤过敏性 

分 类 号：R285.5[医药卫生—中药学]