Synthesis of 2,2-Bis-C-functionalized Chain Glucosid-3-ketals  

作　　者：张福义 刘虹 盛英明 刘宏民 

机构地区：[1]Chemistry Department,The Key Lab of Chemical Biology and Organic Chemistry of Henan Province,Zhengzhou University,Zhengzhou,Henan 450052,China [2]School of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou,Henan 450001,China

出　　处：《Chinese Journal of Chemistry》2012年第1期195-198,共4页中国化学（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China （No. 20972142） and the State Key Laboratory of Bio-organic and Natural Prod- ucts Chemistry, CAS （08417）.

摘　　要：Novel 2,2-bis-C-functionalized chain glucosid-3-uloses have been synthesized in the form of ketal. The synthesis is rather convenient through one pot multistep reactions and no expensive reagents are involved. The products are formed via autoxidation-Michael addition mechanism and their structures were characterized by X-ray crystallographic analysis. Their crystal stuctures are stablilized by intermolecular hydrogen bonds and double-strand supramolecular stacking is observed.Novel 2,2-bis-C-functionalized chain glucosid-3-uloses have been synthesized in the form of ketal. The synthesis is rather convenient through one pot multistep reactions and no expensive reagents are involved. The products are formed via autoxidation-Michael addition mechanism and their structures were characterized by X-ray crystallographic analysis. Their crystal stuctures are stablilized by intermolecular hydrogen bonds and double-strand supramolecular stacking is observed.

关 键 词：2 2-bis-C-functionalized chain glucosid-3-ketal double-strand supramolecular stacking synthesis de-sign crystal structure AUTOXIDATION 

分 类 号：O614.432[理学—无机化学] TS102.311[理学—化学]