An Efficient and Odorless Synthesis of Thioethers Using 2-[Bis（alkylthio）methylene]-3-oxo-N-o-tolylbutanamides as Thiol Equivalents  

作　　者：Yu,Haifeng 

机构地区：[1]Department of Chemistry,Anshan Normal University,Anshan,Liaoning 114007,China

出　　处：《Chinese Journal of Chemistry》2012年第2期367-371,共5页中国化学（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China （No. 20572013） and the Doctoral Foundation of Anshan Normal University.

摘　　要：Using 2-[bis（alkylthio）methylene]-3-oxo-N-o-tolylbutanamides 1 as odorless thiol equivalents, an efficient and odorless synthesis of thioethers has been developed. Promoted by NaOH in EtOH, the cleavage of 1 commences to generate thiolate anions, and the generated thiolate anions then react with halides to give various thioethers in good yield. It is noteworthy that only a very faint odor ofthiols can be perceived during both the reaction and the workup.Using 2-[bis（alkylthio）methylene]-3-oxo-N-o-tolylbutanamides 1 as odorless thiol equivalents, an efficient and odorless synthesis of thioethers has been developed. Promoted by NaOH in EtOH, the cleavage of 1 commences to generate thiolate anions, and the generated thiolate anions then react with halides to give various thioethers in good yield. It is noteworthy that only a very faint odor ofthiols can be perceived during both the reaction and the workup.

关 键 词：a-oxo-ketene dithioacetals odorless thiols equivalents THIOETHERS HALIDES 

分 类 号：TQ225.261[化学工程—有机化工] O623.82[理学—有机化学]