天津市20041名3～6岁入托儿童血脂水平分析  

Blood-lipid levels of 20 041 kindergarten children aged 3 to 6 in Tianjin

作　　者：乔毅娟[1] 王华[1] 刘恩庆[1] 张晓燕[1] 潘蕾[1] 付伯津 王萍[1] 田祯[1] 

机构地区：[1]天津市妇女儿童保健中心,300070

出　　处：《中华流行病学杂志》2012年第3期273-275,共3页Chinese Journal of Epidemiology

摘　　要：目的了解天津市3～6岁儿童血脂水平和血脂异常检出率。方法采集天津市48所幼儿园20041名3～6岁儿童末梢血，采用东芝120全自动生化分析仪检测血浆总胆固醇（TC）和甘油三酯（TG）水平。结果20041名入托儿童TC和TG分别为（4．17±0．69）mmol／L和（0．86±0．44）mmol/L；血脂异常总检出率为11．4％，其中TC异常检出率为7．1％，TG为4．9％，两项均异常的检出率为0．6％。不同性别儿童TC异常检出率女童高于男童，差异有统计学意义（x2=51．77，P〈0．001）。不同年龄组儿童TC和TG异常检出率的差异均有统计学意义（x2=10．29，P=0．016；x2=10．93，P=0．012），但未见明显的年龄变化趋势。不同肥胖程度儿童TC异常检出率的差异无统计学意义，TG异常检出率差异有统计学意义（x2=211．8，P〈0．001），肥胖儿童TG异常检出率明显高于正常和超重儿童。城乡地区儿童TC和TG异常检出率差异均有统计学意义（x2=22．09，P〈0．001；x2=11．26，P=0．001），TC异常检出率城市儿童高于农村，TG异常检出率农村儿童高于城市。结论天津市3～6岁儿童血脂异常率较高，且存在性别、年龄、肥胖程度、地区差异，应有针对性开展儿童血脂异常筛查与干预。Objective To understand the level of blood-lipid and prevalence of dyslipidemia of children aged 3 to 6 in Tianjin, so as to provide evidence for large-scale blood screening strategy and to develop intervention of dyslipidemia and cardiovascular in children. Methods 20 041 children aged 3 to 6 from 48 kindergartens were involved in this study, in Tianjin. Peripheral blood was collected from right leech-finger of these children, after fatless breakfast. Total cholesterol （TC） and triglyceride （TG） of plasma were tested using Toshiba 120 Automatic Biochemical Analyzer. Results The average levels of TC and TG were （4.17 ＋ 0.69）mmol/L and （0.86 ＋__ 0.44） mmol/L in these children. 11.4% of the children had either TC or TG dyslipidemia, with 7.1% had only TC dyslipidemia, 4.9% had only TG dyslipidemia, and 0.6% of them had both TC and TG dyslipidemia. The prevalence of TC dyslipidemia was significantly higher among girls than boys. The prevalence rates of TC dyslipidemia and TG dyslipidemia were different among age groups, but with no significant changes among age groups. The prevalence of TG dyslipidemia was significantly different, with obese children higher than those with normal or overweight children. Different residential areas seemed to be related to the difference on the prevalence of dyslipidemia. Prevalence of TC dyslipidemia was higher in urban than in rural areas. Prevalence of TG dyslipidemia was higher in rural than urban areas. Conclusion The prevalence of dyslipidemia for children aged 3 to 6 was high in Tianjin, and showed differences among genders, age groups and residential regions. Screening and intervention programs on dyslipidemia should be undertaken routinely in children, in order to prevent adult atherosclerosis and coronary heart disease.

关 键 词：血脂异常 儿童 末梢血 

分 类 号：R179[医药卫生—妇幼卫生保健]