布托啡诺复合丙泊酚静脉全麻应用于妇科宫颈锥切的研究  

作　　者：吕文慧[1] 郭强[1] 胡素颖[1] 

机构地区：[1]广东省佛山市顺德区第一人民医院麻醉科,528300

出　　处：《当代医学》2012年第8期82-84,共3页Contemporary Medicine

摘　　要：目的探讨布托啡诺复合丙泊酚用于妇科宫颈锥切的静脉麻醉效果及其安全性。方法将2009年1月～2011年1月妇科中需要进行宫颈锥切的46例患者按照严格随机分组的方式分为布托啡诺复合丙泊酚组(N组)与芬太尼复合丙泊酚(F组),对两组患者手术中呼吸频率、舒张压、收缩压、血氧饱和度进行持续监测,同时观察术后患者意识恢复时间及术中出现的不良反应。N组:于手术诱导前5min先缓慢注射布托啡诺,麻醉诱导开始后5min缓慢注射丙泊酚直至睫毛反应消失;F组:手术开始时便持续注射芬太尼直至手术结束,手术期间芬太尼负荷剂量注射完毕注射丙泊酚。结果与F组相比,N组的麻醉效果显著优于F组,且呼吸循环抑制反应轻,体动少,丙泊酚剂量使用少,患者意识恢复快,并与术者可以进行交流,满意程度较高。术后2h出现恶心、头晕、头痛或下腹疼痛等不良反应方面两组无明显差异。结论布托啡诺与丙泊酚联合应用于妇科宫颈锥切静脉麻醉效果较好,比芬太尼联合丙泊酚更能有效控制麻醉深度,控制手术期间体动反应,且减少丙泊酚用量。Objective To investigate the anesthesia effect and safety of butorphanol compound with propofol in gynecological cervical cone cut. Methods Forty-six cases treated with gynecological cervical cone cut, of which 24 cases were given butorphanol compound with propofol called group N, and 24 cases were treated with fontanel compound with propofol called group F, were enrolled in study. The breathing, systolic blood pressure, diastolic blood oxygen saturation, consciousness recovery time, and adverse reactions were monitored continuously during the operation. Results Compared with group F, group N had more obvious effect of anesthesia. And the respiratory inhibition reaction of group N was much lighter during the operation, the propofol was used in less does moreover there was higher satisfaction in patients, however there were no significantly differences among two groups in adverse reaction. Conclusion Butorphanol combined with propofol has an great effect in anesthesia being applied in gynecological cervical cone cut, of which the anesthetic depth and respiratory inhibition reaction can be controlled at ease.

关 键 词：布托啡诺 丙泊酚 布托啡诺 芬太尼 宫颈锥切 

分 类 号：R614[医药卫生—麻醉学]